BIDIME和BIBOP相關(guān)哌啶簡介上海畢得醫(yī)藥科技供應(yīng)-b2b網(wǎng)站_b2b電子商務(wù)平臺【買產(chǎn)品】-上?？谄蚴称酚邢薰?/title><meta name="description" content="通過在微波輻射下與乙酸酐在乙酸酐存在下通過與醋酸酸酐反應(yīng)易于氰基化的氰基化，以形成相應(yīng)的氰基乙酰胺2a-c，其凝聚用DMF-DMA，形成與肼水合物反應(yīng)的相應(yīng)烯胺4產(chǎn)生氨基吡唑5.此外，氰基乙酰胺2a-c與各種芳基丙二腈反應(yīng)，BIDIME和B"><meta name="keywords" content="BIDIME和BIBOP相關(guān)哌啶簡介,哌啶"><link rel="canonical" href="http://www.cdcfah.com/"/><meta name="applicable-device" content="pc"><link rel="shortcut icon" href="/static/new_net_01/images/favicon.ico"><link rel="stylesheet" href="/static/new_net_01/css/slick.css" /><link rel="stylesheet" href="/static/new_net_01/css/addnew.css"><link rel="stylesheet" href="/static/new_net_01/css/sidenav.css"><link rel="stylesheet" href="/static/new_net_01/css/style.css" /><link rel="stylesheet" href="/static/new_net_01/css/tab.css"><link rel="stylesheet" href="/static/new_net_01/css/404.css"> <meta name="baidu-site-verification" content="OBVzrC9aaQ" /> <meta http-equiv="Cache-Control" 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class="smallimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shbdyykj/637439115872748982/9990792.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="z3bizk3" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價(jià)格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>BIDIME和BIBOP相關(guān)哌啶簡介,哌啶</p><p><span>***更新：</span>2021-01-14 01:22:36</p><p><span id="click" >瀏覽次數(shù)：1次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="b3of87j" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海畢得醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>邱鴻婷</p><p><span>郵箱: </span>3003495196@qq.com</p><p><span>電話: </span>13818398014</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span>https://www.bidepharm.com</p><p><span>手機(jī): </span>021-61629020</p><p><span>地址: </span>翔殷路128號11號樓A座101室</p><p>[當(dāng)前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="rzv7prd" class="page-proshow02"><p class="title">詳細(xì)說明</p><div id="p2y7cie" class="box"><p><p style="text-indent:25px">通過在微波輻射下與乙酸酐在乙酸酐存在下通過與醋酸酸酐反應(yīng)易于氰基化的氰基化，以形成相應(yīng)的氰基乙酰胺2a-c，其凝聚用DMF-DMA，形成與肼水合物反應(yīng)的相應(yīng)烯胺4產(chǎn)生氨基吡唑5.此外，氰基乙酰胺2a-c與各種芳基丙二腈反應(yīng)，BIDIME和BIBOP相關(guān)哌啶簡介，得到一種新的吡啶[1,2-a]噻吩[3,2-e]嘧啶衍生物12a-o。此外，BIDIME和BIBOP相關(guān)哌啶簡介，烯胺4a，b與丙二腈反應(yīng)，得到吡啶[1,2-a]噻吩[3,2-e]嘧啶衍生物19a，b。氰基乙酰胺2a，b也與水楊醛反應(yīng)，得到喹啉衍生物24a，b。此外，氰基乙酰胺2a，b與烯胺酮25a-c反應(yīng)形成相應(yīng)的吡啶-2-一個(gè)衍生物29a-c，BIDIME和BIBOP相關(guān)哌啶簡介。 2A，C與氯化氮氧化鎓氯化物的反應(yīng)提供與氯乙腈反應(yīng)的芳基肼30A，B，以形成無循環(huán)產(chǎn)物31，其不能進(jìn)一步環(huán)化到相應(yīng)的4-氨基吡唑?？梢垣@得七種產(chǎn)品的X射線晶體分析，從而確定在這項(xiàng)工作中的建議結(jié)構(gòu)。測試該研究中的大多數(shù)合成化合物并評估為抗微生物劑。硫代氧化物衍生物作為合成靶雜環(huán)化合物的砌塊，其抗微生物評估。BIDIME和BIBOP相關(guān)哌啶簡介</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="BIDIME和BIBOP相關(guān)哌啶簡介,哌啶" src="https://tyunfile.71360.com/WaterMark/UploadFile/shbdyykj/637439115872748982/9990792.png"></div><p style="text-indent:25px">哌啶是含有一個(gè)N原子的六元環(huán)，可以認(rèn)為是吡啶和氫的反應(yīng)產(chǎn)物。一些哌啶化合物及其衍生物具有良好的生物學(xué)活性，例如殺蟲，殺菌，除草和抗植物病毒活性。其中一些化合物用于農(nóng)藥，藥物，染料和其他精細(xì)化工行業(yè)。在醫(yī)學(xué)領(lǐng)域，哌啶基是天然產(chǎn)物生物堿的一種成分，例如止痛藥哌替啶；在農(nóng)藥領(lǐng)域，例如地美哌酸鹽和胡椒粉已被***用于防治稻田中的n和洋蘭。）和煙堿殺蟲劑哌啶在我國制造。目前，關(guān)于國內(nèi)外哌啶類化合物的總體情況尚無報(bào)道。上海螺環(huán)哌啶3,3,3-三氟氟化物與脒的反應(yīng) - 新型三氟甲基取代的雜環(huán)基塊。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="BIDIME和BIBOP相關(guān)哌啶簡介,哌啶" src="https://tyunfile.71360.com/WaterMark/UploadFile/shbdyykj/637439115881254773/2914049.png"></div><p style="text-indent:25px">1,6-二氨基-4-甲基-2-氧代-1-H-吡啶-3,5-二羰基腈1與苯基異氰酸苯酯和異硫氰酸酯衍生物反應(yīng)，分別產(chǎn)生三唑吡啶衍生物4和5A-C.用三乙酯反流的回流提供亞氨基醚6，在乙醇鈉中煮沸，將其環(huán)化至7。用碳二硫化碳的1和亞硝酸鈉的反應(yīng)產(chǎn)生四唑噠嗪9.化合物1可以在與α-鹵代羰基化合物反應(yīng)后向相應(yīng)的吡啶嗪衍生物10-14結(jié)合。通過用元素硫的化合物1反應(yīng)獲得噻吩吡啶15。報(bào)告了15種開發(fā)寬方便的途徑的適用性和合成潛力，以獨(dú)特的多官能取代的異喹啉衍生物進(jìn)行。因此，化合物15與不同的糖硫磷反應(yīng)以分別產(chǎn)生異醌衍生物17-22。描述了新合成的結(jié)構(gòu)的化學(xué)和光譜驗(yàn)證。</p><p style="text-indent:25px">許多吡啶硫酮具有生物活性?？紤]到對利用容易獲得的烯胺酮作為起始原料開發(fā)多官能取代的雜芳族化合物的有效合成的興趣。因此，用氰基硫代乙酰胺或氰基乙酰胺處理烯胺酮3得到吡啶硫酮5a和吡啶酮5b?；衔镌诨亓鞯囊掖尖c中與α-鹵代酮反應(yīng)，得到噻吩并吡啶衍生物。化合物5a與碘甲烷反應(yīng)得到2-甲基硫代吡啶。吡啶硫酮5a與二甲基甲酰胺-二甲基乙縮醛縮合得到加合物，與水合肼得到?；衔?a與芳基亞甲基腈反應(yīng)得到苯乙烯基衍生物14a-d。化合物14a-d也是在相同條件下由5a與芳族醛縮合制備的。噻吩并吡啶衍生物9a-d與原甲酸三乙酯，乙酸酐，二硫化碳和亞硝酸鈉的回流，分別得到化合物。氨基吡唑12在回流的DMF中與二甲基氨基苯乙酮鹽酸鹽24或烯胺酮30反應(yīng)，得到化合物26a-d?；衔锱cDMF-DMA反應(yīng)得到，其與化合物反應(yīng)得到直接由12與烯胺酮反應(yīng)制備的38 2.用亞硝酸將12重氮化，然后與不同的活性亞甲基試劑偶聯(lián)，得到吡啶并噻吩并三嗪42a，b。亞芐基苯乙酮與12的反應(yīng)產(chǎn)生吡啶并吡唑并嘧啶44?；衔?2也直接與活性亞甲基反應(yīng)，得到吡啶并吡唑并嘧啶衍生物46a，b。一種雜環(huán)砌塊的方法：合成含有[5,6]吡喃[2,3-C]吡唑-4（1H）- 酮部分的新型環(huán)形系統(tǒng)。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="BIDIME和BIBOP相關(guān)哌啶簡介,哌啶" src="https://tyunfile.71360.com/WaterMark/UploadFile/shbdyykj/637439115893520388/4013149.png"></div><p style="text-indent:25px">哌啶，無色液體。哌啶,用作溶劑、有機(jī)合成中間體、環(huán)氧樹脂交聯(lián)劑、縮合催化劑等。有像胡椒的氣味。能與水混溶，溶于乙醇、**、**及苯。35%哌啶的恒沸水溶液沸點(diǎn)為92.8℃；pKa11.1；堿性略強(qiáng)于吡啶。與酸成鹽，化學(xué)性質(zhì)與脂肪仲胺相似一種強(qiáng)有機(jī)堿，與無機(jī)酸作用生成鹽。能與蒸汽一同揮發(fā)。用于制藥，主要是鹽酸哌啶和硝酸哌啶（片狀晶體，熔點(diǎn)110℃）。也用于其他有機(jī)合成，并用作環(huán)氧樹脂的熟化劑等。由吡啶經(jīng)氫化而制得。具有較強(qiáng)的還原性。用于有機(jī)半導(dǎo)體的雜環(huán)砌塊。Walphos相關(guān)哌啶化合物價(jià)格</p><p style="text-indent:25px">P = C鍵作為三元雜環(huán)陽離子的砌塊：合成，結(jié)構(gòu)和機(jī)械研究。BIDIME和BIBOP相關(guān)哌啶簡介</p><p style="text-indent:25px">哌啶是從植物Psilocaulon absimile（Aizoaceae）和Petrosimonia monandra中獲得的。哌啶被微生物代謝，可能被用作控制根莖內(nèi)細(xì)菌種群的抗菌劑。哌啶是有機(jī)化合物合成中***使用的結(jié)構(gòu)單元和化學(xué)試劑，包括血管擴(kuò)張劑和抗***藥等藥物（PMID：25255204）。哌啶是一種***使用的仲胺，用于將酮轉(zhuǎn)化為烯胺。衍生自哌啶的烯胺可用于鸛烯胺烷基化反應(yīng)。哌啶用作溶劑和堿。對于某些衍生物也是如此：N-甲?；哙な且环N極性非質(zhì)子溶劑，具有比其他酰胺溶劑更好的烴溶解度； 2,2,6,6-四甲基哌啶是高度位阻的堿，由于其低親核性和高溶解度而有用在有機(jī)溶劑中。BIDIME和BIBOP相關(guān)哌啶簡介</p><p> 上海畢得醫(yī)藥科技有限公司成立于2007年，總部位于上海市楊浦區(qū)理工大學(xué)國家大學(xué)科技園，是一家以醫(yī)藥中間體相關(guān)產(chǎn)品的研發(fā)、生產(chǎn)、銷售及合成定制為主的****。自公司成立以來，始終堅(jiān)持信譽(yù)至上，質(zhì)量過硬的企業(yè)信條，產(chǎn)品被應(yīng)用于生命科學(xué)、有機(jī)化學(xué)、材料科學(xué)、分析化學(xué)與其他學(xué)科的研發(fā)及生產(chǎn)領(lǐng)域，銷售范圍遍及全球。目前，公司與諸多國內(nèi)**醫(yī)藥研發(fā)單位建立了合作伙伴關(guān)系。 </p> <p> 公司位于上海理工大學(xué)科技園的行政辦公中心面積達(dá)1,700平米，在藥谷設(shè)立的研發(fā)中心面積1,800平米，包括化學(xué)合成實(shí)驗(yàn)室和公斤級實(shí)驗(yàn)室，并配有現(xiàn)代化倉儲物流中心。公司優(yōu)勢產(chǎn)品包括特色雜環(huán)化合物、含氟化合物、手性化合物、氨基酸及其衍生物、硼酸及其衍生物等，已有多項(xiàng)科研項(xiàng)目獲得國家發(fā)明專利。 </p> <p> 為確保產(chǎn)品質(zhì)量，公司引進(jìn)了先進(jìn)齊全的分析測試設(shè)備，包括400MHz核磁共振儀(NMR)、電感耦合等離子體發(fā)射光譜儀(ICP)、液質(zhì)聯(lián)用儀(LCMS)等，并配以嚴(yán)格的質(zhì)量管理體系。公司簽有具備GMP資質(zhì)的合作工廠，配備專業(yè)的研發(fā)團(tuán)隊(duì)，形成了從小試、中試到工業(yè)化規(guī)模的生產(chǎn)能力，滿足客戶定制合成、目錄試劑采購及合成外包生產(chǎn)的需求。 </p></p><br /><p>文章來源地址: http://www.cdcfah.com/cp/2833800.html</p></div></div></div></div></div><div id="pse27hn" class="page-right twoColRt"><div id="kiz8q8e" class="box01 margin10 clearfix"><h3><a href="http://www.cdcfah.com/cp/">猜你喜歡</a></h3><div id="cl7wn82" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/814588.html"><div><img src="http://tyunfile.71360.com/UpLoadFile/2019/11/1/14/637082168864691056_lgpj_5374157.jpg" alt="福建ZF配件哪家強(qiáng) 信息推薦自業(yè)物資供應(yīng)" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></div><p>福建ZF配件哪家強(qiáng) 信息推薦自業(yè)物資供應(yīng)</p></a></div><div id="sp7qne2" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/846569.html"><div><img 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