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src="https://tyunfile.71360.com/WaterMark/UploadFile/shbdyykj/637439115831694514/5506440.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="i3qmyp9" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價(jià)格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>上海PHOX哌啶,哌啶</p><p><span>***更新：</span>2021-01-15 03:14:34</p><p><span id="click" >瀏覽次數(shù)：5次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="jq2jqcq" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海畢得醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>邱鴻婷</p><p><span>郵箱: </span>3003495196@qq.com</p><p><span>電話: </span>13818398014</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span>https://www.bidepharm.com</p><p><span>手機(jī): </span>021-61629020</p><p><span>地址: </span>翔殷路128號(hào)11號(hào)樓A座101室</p><p>[當(dāng)前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="k7iuqs9" class="page-proshow02"><p class="title">詳細(xì)說明</p><div id="ornght9" class="box"><p><p style="text-indent:25px">通過2-乙?；?3-甲基的反應(yīng)制備未報(bào)告的2- [E-3-（N，N-二甲基氨基）丙烯酰基] -3-甲基-5，上海PHOX哌啶,6-二苯基咪唑并[2,1-b]噻唑3 -5，6-二苯基咪唑并[2，1-b]噻唑2與二甲基甲酰胺二甲基乙縮醛（DMF-DMA）。 Enaminone 3與腈亞胺5a-f進(jìn)行區(qū)域選擇性的1,3-偶極環(huán)加成反應(yīng)，得到相應(yīng)的吡唑7a-f。 7a，d，g與水合肼反應(yīng)，分別得到吡唑并[3，4-d]噠嗪8a-c。烯胺3也與肼，鹽酸羥胺，上海PHOX哌啶，5-氨基吡唑11，上海PHOX哌啶、6-氨基硫尿嘧啶15和馬尿酸22反應(yīng)。新合成的化合物的結(jié)構(gòu)通過光譜數(shù)據(jù)和元素分析得到證實(shí)。氟代官能化聚合物正雜環(huán)碳烯 - 鋅絡(luò)合物：用CO 2作為C1建筑塊的丙氨酸甲基化和甲基化的有效催化劑。上海PHOX哌啶</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="上海PHOX哌啶,哌啶" src="https://tyunfile.71360.com/WaterMark/UploadFile/shbdyykj/637439115831694514/5506440.png"></div><p style="text-indent:25px">乙酰乙酰苯胺1與DMF-DMA反應(yīng)，得到烯胺酮2。化合物2，在用肼處理時(shí)，分別得到吡唑4a和4b，與吡唑衍生物5a和56處理時(shí)的吡唑并嘧啶7。另一方面，2與苯并咪唑反應(yīng) 形成苯并咪唑-2-乙腈，嘧啶基苯并咪唑14和吡啶基苯并咪唑17。 2在沸騰的乙酸酐中與馬尿酸反應(yīng)，得到吡啶20。在2與丙二腈的反應(yīng)中，生成氰基乙酰胺或丙二腈的二聚體化合物21、22和24。使化合物22與芳基丙二腈進(jìn)一步反應(yīng)，得到苯并吡啶衍生物28.用S-DMF混合物處理的吡啶酮22得到噻吩并吡啶29，同時(shí)與DMFDMA回流得到吡啶并吡啶30。手性氮哌啶應(yīng)用呋喃布吡喃丙烷的總合成。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="上海PHOX哌啶,哌啶" src="https://tyunfile.71360.com/WaterMark/UploadFile/shbdyykj/637439115825239454/6107741.png"></div><p style="text-indent:25px">以氟代咪唑鎓鹽為前體，經(jīng)兩步烷基化反應(yīng)，設(shè)計(jì)合成了一種含氟官能團(tuán)的聚合N-雜環(huán)卡賓（NHC）-Zn配合物（F-PNHC-Zn）。所得的F-PNHC-Zn用于在有機(jī)硅烷存在下使用CO2作為C1結(jié)構(gòu)單元來催化胺的甲?；图谆谙嗤瑮l件下，其顯示出比相應(yīng)的無氟PNHC-Zn高得多的活性。具有吸電子基團(tuán)和給電子基團(tuán)的N-甲基苯胺都可以> 90％的轉(zhuǎn)化率轉(zhuǎn)化為相應(yīng)的甲酰胺和甲胺。即使在非常低的CO2壓力下（用N-2稀釋0.05 MPa）也可以實(shí)現(xiàn)N-甲基苯胺的定量轉(zhuǎn)化。而且，F(xiàn)-PNHC-Zn對(duì)于這些反應(yīng)非常穩(wěn)定并且易于回收。</p><p style="text-indent:25px">作為在合成各種生物重要性的雜物中的持續(xù)研究的一部分，從6-Iodo-2-異丙基-4H-3,1-苯并惡化-4-3的新化合物合成的有效和方便的方法-one 1作為砌塊。苯并嗪酮1與各種試劑如二乙基acetone，疊氮化鈉和磷戊磺酰胺的反應(yīng)產(chǎn)生了化合物2-5。研究了苯并噻嗪-4-倍硫醚5朝甲酰胺和肼水合物的行為，形成了喹唑啉酮衍生物8與β-D-葡萄糖五乙酸，乙基2-甲基-5 - （（1s，2r ，3R）-1,2,3,4-四羥基丁基）呋喃-3-羧酸鹽，表氯醇和苯二磺酰氯，得到喹唑啉酮衍生物9,10,12和13。喹唑啉酮衍生物10與乙酸酐的反應(yīng)導(dǎo)致形成?；衔?1.通過與苯甲酰phenylacetic acid 乙酯，硫氰酸鉀和苯基異硫氰酸苯磺酸的反應(yīng)來研究喹唑苯基酰肼衍生物衍生物14的行為（[16]）。喹唑啉酮衍生物分別為15,16和18。用氫氧化鈉處理化合物16，然后得到鹽酸，得到巰基 - 三唑衍生物17.通過元素分析，紅外（IR），H-1 NMR，C-13 NMR和質(zhì)譜證實(shí)了新合成的化合物的結(jié)構(gòu)。預(yù)先評(píng)估一些合成化合物的抗微生物活性。1-（N，N-二甲基氨基）-2-（N-苯基氨基?；?1-丁烯-3-作為合成雜環(huán)化合物的砌塊。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="上海PHOX哌啶,哌啶" src="https://tyunfile.71360.com/WaterMark/UploadFile/shbdyykj/637439115895268337/1133578.png"></div><p style="text-indent:25px">描述了由具有氧代和甲基磺基核鍵組成的亞ZenetetrayL亞基組成的梯形聚合物的合成途徑。作為具有側(cè)鏈甲基磺?；年P(guān)鍵中間體，聚（亞苯基氧化物）S通過用O-2的相應(yīng)酚的銅催化的氧化聚合制備。在乙酸存在下，在乙酸存在下具有等摩爾量的H 2 O 2的聚合物的氧化作用于不形成不需要的甲基磺基的甲基磺?；鶎?duì)甲基磺?；母弋a(chǎn)轉(zhuǎn)化。在稀釋條件下所得聚合物（芳基磺氧化芳基芳基反應(yīng)）的超?；s合誘導(dǎo)羥甲基苯基磺酸鹽的聚合物 - 類似的分子內(nèi)親電子閉合反應(yīng)在相鄰的苯環(huán)上，得到所需的梯形聚合物，證明是a半導(dǎo)體具有2×10（5）S / cm的固有電導(dǎo)率。梯子聚合物與模型化合物的光譜性質(zhì)的比較，如5-甲基苯并辛酸二甲酸甲酸乙酯和苯甲酰胺，公開了在甲基磺基核鍵上的PI-Electron Delocalization，展示了梯化對(duì)P-PI / D-PI相互作用的療效芳基磺酸部分。這種合成方法允許硫代和烷基磺基梯梯形膠合劑，用于各種苯基醚以高產(chǎn)率形成。2-氨基噻吩作為雜環(huán)合成中的砌塊。手性氨基膦哌啶產(chǎn)品</p><p style="text-indent:25px">哌啶. 英文名稱. Piperidine.上海PHOX哌啶</p><p style="text-indent:25px">3-芳基/雜芳基-2-芳基羥基芳基-3-氧化丙烷2c，d用乙基三苯基膦酰基磷酸乙酯D的Wittig反應(yīng)在甲基磺酰甲基碳酸甲基甲基己?；刑峁?-取代的6-芳亞吡嗪-3（2H） - 酮（5A，B）中等產(chǎn)量。在乙酸鉀存在下，也從2C，D與乙酸酐的反應(yīng)獲得化合物5A，B. 1-取代-3-二甲基氨基丙醇-2-烯-1-氨基丙醇1B，D夫婦與5-甲基異惡唑-3-重氮氯化氫，得到異惡唑肼唑烷丙烷2g，h?；衔?a，b耦合加入5-甲基吡唑-3-重氮酰氯，得到吡唑基酰肼丙烷，其容易循環(huán)到相應(yīng)的吡唑[5,1-C] [1,2,4]三嗪。研究了2-芳基?；?3-氧化丙烷2A-F朝向各種活性亞甲基試劑的反應(yīng)性。上海PHOX哌啶</p><p> 上海畢得醫(yī)藥科技有限公司成立于2007年，總部位于上海市楊浦區(qū)理工大學(xué)國家大學(xué)科技園，是一家以醫(yī)藥中間體相關(guān)產(chǎn)品的研發(fā)、生產(chǎn)、銷售及合成定制為主的****。自公司成立以來，始終堅(jiān)持信譽(yù)至上，質(zhì)量過硬的企業(yè)信條，產(chǎn)品被應(yīng)用于生命科學(xué)、有機(jī)化學(xué)、材料科學(xué)、分析化學(xué)與其他學(xué)科的研發(fā)及生產(chǎn)領(lǐng)域，銷售范圍遍及全球。目前，公司與諸多國內(nèi)**醫(yī)藥研發(fā)單位建立了合作伙伴關(guān)系。 </p> <p> 公司位于上海理工大學(xué)科技園的行政辦公中心面積達(dá)1,700平米，在藥谷設(shè)立的研發(fā)中心面積1,800平米，包括化學(xué)合成實(shí)驗(yàn)室和公斤級(jí)實(shí)驗(yàn)室，并配有現(xiàn)代化倉儲(chǔ)物流中心。公司優(yōu)勢(shì)產(chǎn)品包括特色雜環(huán)化合物、含氟化合物、手性化合物、氨基酸及其衍生物、硼酸及其衍生物等，已有多項(xiàng)科研項(xiàng)目獲得國家發(fā)明專利。 </p> <p> 為確保產(chǎn)品質(zhì)量，公司引進(jìn)了先進(jìn)齊全的分析測(cè)試設(shè)備，包括400MHz核磁共振儀(NMR)、電感耦合等離子體發(fā)射光譜儀(ICP)、液質(zhì)聯(lián)用儀(LCMS)等，并配以嚴(yán)格的質(zhì)量管理體系。公司簽有具備GMP資質(zhì)的合作工廠，配備專業(yè)的研發(fā)團(tuán)隊(duì)，形成了從小試、中試到工業(yè)化規(guī)模的生產(chǎn)能力，滿足客戶定制合成、目錄試劑采購及合成外包生產(chǎn)的需求。 </p></p><br /><p>文章來源地址: http://www.cdcfah.com/cp/2851260.html</p></div></div></div></div></div><div id="cuv3vm9" class="page-right twoColRt"><div id="b8vhiut" class="box01 margin10 clearfix"><h3><a href="http://www.cdcfah.com/cp/">猜你喜歡</a></h3><div id="aned7xl" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/814588.html"><div><img src="http://tyunfile.71360.com/UpLoadFile/2019/11/1/14/637082168864691056_lgpj_5374157.jpg" alt="福建ZF配件哪家強(qiáng) 信息推薦自業(yè)物資供應(yīng)" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></div><p>福建ZF配件哪家強(qiáng) 信息推薦自業(yè)物資供應(yīng)</p></a></div><div id="knelmty" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/846569.html"><div><img 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