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clearfix"><section class="container clearfix tcPro"><section class="home-main container clearfix"><div id="2oq7lv3" class="twoCol"><div id="qz3i8t7" class="page-proshow clearfix"><p class="current"> 當(dāng)前位置:<a href="http://www.cdcfah.com/">首頁?<a href="http://www.cdcfah.com/cp/">產(chǎn)品供應(yīng)</a>?<a href="http://www.cdcfah.com/cp/second-_yyby/">醫(yī)藥健康</a>?<a href="http://www.cdcfah.com/cp/third-yyby_yyxmhz/">醫(yī)藥項(xiàng)目合作</a>?河北蜂毒供應(yīng)廠家上海臨辰供應(yīng)</p><div id="3urolcb" class="leftbox clearfix"><h1>河北蜂毒供應(yīng)廠家上海臨辰供應(yīng)</h1><div id="qp7lvht" class="proBig"><div id="ibyqxeg" class="bigimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637291455616943360/3384309.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div><div id="d8f2zgi" class="smallimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637291455616943360/3384309.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="333kgta" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價(jià)格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>河北蜂毒,蜂毒</p><p><span>***更新：</span>2021-01-12 04:10:13</p><p><span id="click" >瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="jfmjb8f" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海臨辰醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>葉海岑</p><p><span>郵箱: </span>info@linchenpharm.com</p><p><span>電話: </span>13761181955</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span></p><p><span>手機(jī): </span>021-31606595</p><p><span>地址: </span>辰花路5088弄221號(hào)</p><p>[當(dāng)前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="pjbt8pe" class="page-proshow02"><p class="title">詳細(xì)說明</p><div id="u87myah" class="box"><p><p> 蜂毒肽呈強(qiáng)堿性(pH=10)，易溶于水，它在蜂毒中起主要的藥理作用，是目前人類所知***性**強(qiáng)的物質(zhì)之一。它具有類似***的作用，卻不具有***的不良反應(yīng)。此外，亦具抑菌、抗輻射、抗病毒等作用。蜂毒肽還可以刺穿**毒的保護(hù)外層，毀滅**毒，但又不傷及周圍正常細(xì)胞。近年來又有對(duì)其***作用進(jìn)行研究的報(bào)道。但是其臨床應(yīng)用卻有很多局限，主要原因是現(xiàn)有技術(shù)難以將蜂毒中有致敏反應(yīng)并與蜂毒肽分子量接近的磷脂酶A2完全去除，河北蜂毒。 </p> <p> 人類社會(huì)利用蜂毒的歷史悠久，河北蜂毒，同時(shí)人們對(duì)蜂毒和蜂毒肽的研究也在不斷深入。自從1952年Neuman等人用電泳法分離獲得蜂毒肽以來，關(guān)于蜂毒肽的研究拉開了帷幕，河北蜂毒，很多研究發(fā)現(xiàn)蜂毒肽對(duì)體內(nèi)外多種**細(xì)胞都有殺傷作用。用于工業(yè)生產(chǎn)的蜂毒主要有兩種。河北蜂毒</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="河北蜂毒,蜂毒" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637291455616943360/3384309.png"></div><p> 蜂毒中的磷脂酶A皇約占全毒于重的8％～l2％，由128個(gè)氨基酸組成磷脂酶活性較高，水解磷脂的脂肪鏈，使卵磷脂成為溶血卵磷脂起間接溶血作用．是間接溶血毒： </p> <p> 蜂毒的藥理研究 </p> <p> 對(duì)神經(jīng)系統(tǒng)的作用蜂毒是向神經(jīng)性的，在大腦網(wǎng)狀組織}具有阻滯作用和溶膽堿活性，并能改變皮層的生物電活性、尤其是蜂毒肽對(duì)N一膽堿受體有選擇性阻滯作用，可使***系統(tǒng)突觸內(nèi)興奮傳導(dǎo)阻滯。 </p> <p> ***作用蜂毒肽能***20～30種革蘭陽性和陰***原微生物的生長(zhǎng)繁殖，并能對(duì)抗對(duì)青霉素耐藥的金黃色葡萄球菌，還能增強(qiáng)磺胺類和青霉素類***的***斂力一 </p> <p> <br /> 河北蜂毒由于蜂毒來源豐富．作用廣，功效大，因此蜂毒的藥理作用和***價(jià)值將會(huì)有一個(gè)廣悶發(fā)展前景。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="河北蜂毒,蜂毒" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637291455992314454/6782377.png"></div><p> 1999年，Kubo等通過5種細(xì)胞毒的測(cè)定方法對(duì)蜂毒肽與嗜酸性粒細(xì)胞的主要堿性蛋白進(jìn)行比較，結(jié)果證實(shí)蜂毒肽能插入K562細(xì)胞的胞膜中進(jìn)而形成孔道，引起Ca內(nèi)流，使胞內(nèi)Ca濃度升高，細(xì)胞裂解。1小時(shí)內(nèi)，蜂毒肽對(duì)實(shí)驗(yàn)的白血病細(xì)胞均具殺傷效果。Shamsher等研究發(fā)現(xiàn)蜂毒肽可***磷酸脂酶D進(jìn)而裂解人單核白血病細(xì)胞(U937)。 </p> <p> <br /> </p> <p> 2000年，王關(guān)林等從蜜蜂毒腺中提取總RNA，通過RT-PCR方法擴(kuò)增得到了蜂毒肽前體蛋白的cDNA，再進(jìn)一步通過定點(diǎn)誘變?cè)诜涠倦男蛄星耙肓私?jīng)胺裂解位點(diǎn)，構(gòu)建了與β-半乳糖苷酶部分序列相融合的蜂毒肽誘變蛋白表達(dá)載體，序列分析結(jié)果表明，他們成功地引入了目的密碼子，且與β-半乳糖苷酶部分序列構(gòu)成正確的讀碼框，并在大腸桿菌中表達(dá)了誘變蛋白。 </p><p style="text-indent:25px">分子的3個(gè)賴氨酸和2個(gè)精氨酸殘基使其成為強(qiáng)堿性肽，在中性水溶液中，蜂毒肽作為單體是以隨機(jī)的卷曲結(jié)構(gòu)存在的，而隨著pH值以及離子強(qiáng)度的增高，蜂毒肽自我交聯(lián)，形成螺旋的四聚體結(jié)構(gòu)，有研究發(fā)現(xiàn)在不同的溶液中蜂毒肽的螺旋結(jié)構(gòu)區(qū)域及螺旋間的角度是不同的。螺旋結(jié)構(gòu)中前21個(gè)氨基酸是極性的，位于螺旋的表面，而非極性氨基酸在螺旋的另一面。其兩親性(am-phiphilie)是膜結(jié)合肽和膜蛋白跨膜螺旋的特征。所以這個(gè)特性決定蜂毒肽既可以溶于水中，又可以與膜自然結(jié)合，進(jìn)而溶解細(xì)胞。蜂毒中富含的蜂毒明肽可直接作用于***系統(tǒng)并能***神經(jīng)興奮。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="河北蜂毒,蜂毒" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637291455967539063/1397395.png"></div><p> 一、取毒對(duì)象 </p> <p> <br /> </p> <p> 蜂毒是工蜂尾部毒囊排出的透明毒液(蜂王和雄蜂沒0腺而不能生產(chǎn)蜂毒)，工蜂在剛出房時(shí)毒囊中只有極少量的蜂毒，之后隨著日齡增長(zhǎng)毒囊中的毒液也會(huì)逐漸增多，但18日齡后毒囊中的毒液便會(huì)停止增長(zhǎng)，此時(shí)1只工蜂大約可以生產(chǎn)0.3毫克蜂毒，因此蜂毒的采集對(duì)象主要是18日齡后的成年工蜂。 </p> <p> <br /> </p> <p> 蜜蜂 </p> <p> <br /> </p> <p> 二、操作原理 </p> <p> <br /> </p> <p> 蜂毒**常用的采集方法是電刺激法，原理是工蜂受到弱電流刺激時(shí)會(huì)產(chǎn)生蟄刺和排毒的反射行為，此時(shí)若能將工蜂排出的毒液收集起來便可得到較為純凈的蜂毒，而且電刺激法取毒相對(duì)于其他取毒方法而言對(duì)工蜂的傷害非常小，采用這種方法取毒后工蜂并不會(huì)死亡，只是工蜂的毒囊中沒0液而已。蜂毒是醫(yī)藥及生物工程方面的重要原料。河北蜂毒</p><p style="text-indent:25px">：蜂毒為復(fù)雜混合物，藥理作用比較多，已*** 應(yīng)用于臨床。河北蜂毒</p><p> 六、謹(jǐn)防過敏 </p> <p> 蜂毒含有大量的致過敏性物質(zhì)，雖然對(duì)普通人而言不會(huì)出現(xiàn)嚴(yán)重的影響，但對(duì)過敏性體質(zhì)者來說則極有可能出現(xiàn)過敏現(xiàn)象，嚴(yán)重時(shí)甚至可能危及生命，因此在使用蜂毒前一定要進(jìn)行過敏性檢測(cè)，另外腎功能衰竭、造血系統(tǒng)疾患、孕婦等人群為了確保安全也比較好不要使用蜂毒。 </p> <p> 總結(jié)：蜂毒是蜜蜂自衛(wèi)的“化學(xué)武器”，但事實(shí)上蜜蜂的毒性是非常弱的，除了過敏體質(zhì)者外一般人被蜜蜂蟄后過1～2天便會(huì)痊愈，而且偶爾被蜜蜂蟄刺對(duì)健康反而有一定的好處，目前比較流行的蜂療便來源于此。 </p> <p> <br /> 河北蜂毒</p></p><br /><p>文章來源地址: 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