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class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336263828125/6823745.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div><div id="7ax32ky" class="smallimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336263828125/6823745.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="ti9vxe9" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>D-泛酸鈣泛解酸內(nèi)酯批發(fā)價</p><p><span>***更新：</span>2020-06-17 21:30:09</p><p><span id="click" >瀏覽次數(shù)：6次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="txmdax9" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海臨辰醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>葉海岑</p><p><span>郵箱: </span>info@linchenpharm.com</p><p><span>電話: </span>13761181955</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span></p><p><span>手機: </span>021-31606595</p><p><span>地址: </span>辰花路5088弄221號</p><p>[當前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="wqvcjv9" class="page-proshow02"><p class="title">詳細說明</p><div id="esu2qx4" class="box"><p><p> D-泛酸鈣，D-泛酸鈣泛解酸內(nèi)酯批發(fā)價，化學名為N-(α,γ-二羥基-β,β-二甲基丁酰)-β-氨基丙酸鈣，俗稱維生素B5，是輔酶A的組成部分，它是人體和動物維持正常生理機能不可缺少的物質(zhì)，廣泛應(yīng)用于飼料、醫(yī)藥、食品等工業(yè)。 </p> <p> D-泛醇，俗稱維生素原B5，是一種優(yōu)異的皮膚與頭發(fā)保護劑，可使皮膚保持柔嫩、毛發(fā)光亮油潤，D-泛酸鈣泛解酸內(nèi)酯批發(fā)價，D-泛酸鈣泛解酸內(nèi)酯批發(fā)價，廣泛應(yīng)用在護發(fā)產(chǎn)品和化妝品中，還可用于醫(yī)藥、保健食品等領(lǐng)域。 </p> <p> D-泛酸鈣的制備方法主要有以下兩種。 </p> <p> 一種是先化學合成DL-泛酸鈣，通過拆分DL-泛酸鈣而制得D-泛酸鈣。 </p> <p> 另一種是通過化學法或生物法拆分關(guān)鍵中間體DL-泛解酸內(nèi)酯得到D-泛解酸內(nèi)酯，再由D-泛解酸內(nèi)酯與β--氨基丙酸反應(yīng)合成D-泛酸鈣。 </p> <p> D-泛醇由D-泛解酸內(nèi)酯與β--氨基丙醇反應(yīng)制得。 </p> <p> <br /> </p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="D-泛酸鈣泛解酸內(nèi)酯批發(fā)價" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336263828125/6823745.png"></div><p style="text-indent:25px">水解酶催化選擇性拆分制備D-泛解酸內(nèi)酯DL-泛解酸內(nèi)酯可經(jīng)手性拆分得到所需要的D-泛解酸內(nèi)酯?；瘜W法拆分所需的化學拆分劑或結(jié)晶操作一般較為昂貴，而利用水解酶催化的動力學拆分，具有節(jié)能環(huán)保、產(chǎn)品光學純度高等優(yōu)點，更適用于工業(yè)生產(chǎn)。水解酶選擇性水解泛解酸內(nèi)酯，根據(jù)選擇性可分為L-泛解酸內(nèi)酯水解酶和D-泛解酸內(nèi)酯水解酶。DL-泛解酸內(nèi)酯經(jīng)L-泛解酸內(nèi)酯水解酶水解，留下D-泛解酸內(nèi)酯，產(chǎn)生的L-泛解酸再經(jīng)化學內(nèi)酯、外消旋轉(zhuǎn)為DL-泛解酸內(nèi)酯。已知的L-泛解酸內(nèi)酯水解酶，大多來源于細菌，如多形無色桿菌、蘇云金芽孢桿菌、放射性土壤桿菌、根*農(nóng)桿菌。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="D-泛酸鈣泛解酸內(nèi)酯批發(fā)價" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336133632812/8293857.png"></div><p style="text-indent:25px">其中Kataoka M 等發(fā)現(xiàn)來源于根*農(nóng)桿菌的L-泛解酸內(nèi)酯水解酶有較高的活力和選擇性。Kesseler M 等對根*農(nóng)桿菌lu678 的L-泛解酸內(nèi)酯水解酶構(gòu)建大腸工程菌并過量表達該蛋白，酶活提高了200 倍，達到600 U/g。該過程要求L-泛解酸內(nèi)酯必須完全水解，才能獲得高光學純度的D-泛解酸內(nèi)酯，限制了其工業(yè)應(yīng)用。D-泛解酸內(nèi)酯水解酶選擇性水解拆分DL-泛解酸內(nèi)酯生成D-泛解酸，再經(jīng)內(nèi)酯化生成D-泛解酸內(nèi)酯，留下的L-泛解酸內(nèi)酯經(jīng)化學消旋化為DL-泛解酸內(nèi)酯重新循環(huán)拆分。D-泛解酸內(nèi)酯水解酶來源豐富，其中**常用的是鐮飽霉菌，有尖孢鐮刀菌、腐皮鐮刀菌和串珠鐮刀菌。2007 年，SAKAMOTO K等利用固定化的尖孢鐮刀菌來水解拆分DL-泛解酸內(nèi)酯，固定化細胞的半衰期可以達到6 000h，經(jīng)過180次重復(fù)利用后仍然保持原活力的71%，相對于游離的整細胞催化其半衰期提高了35 倍。</p></p><br /><p>文章來源地址: http://www.cdcfah.com/cp/294226.html</p></div></div></div></div></div><div id="pjbt8pr" class="page-right twoColRt"><div id="vkc7d77" class="box01 margin10 clearfix"><h3><a href="http://www.cdcfah.com/cp/">猜你喜歡</a></h3><div id="od24xpe" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/814588.html"><div><img src="http://tyunfile.71360.com/UpLoadFile/2019/11/1/14/637082168864691056_lgpj_5374157.jpg" alt="福建ZF配件哪家強信息推薦自業(yè)物資供應(yīng)" class="vcenter" 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