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"index_product"><a href="http://www.cdcfah.com/cp/"><span>產(chǎn)品供應(yīng)</span></a></li><li id = "index_news"><a href="http://www.cdcfah.com/zx/"><span>新聞資訊</span></a></li><li id = "index_article"><a href="http://www.cdcfah.com/xw/"><span>行業(yè)資訊</span></a></li><li id = "index_show"><a href="http://www.cdcfah.com/zh/"><span>展會(huì)信息</span></a></li></ul></div></nav><section class="wrap clearfix"><section class="container clearfix tcPro"><section class="home-main container clearfix"><div id="r3g7lx8" class="twoCol"><div id="wkceb4c" class="page-proshow clearfix"><p class="current"> 當(dāng)前位置:<a href="http://www.cdcfah.com/">首頁?<a href="http://www.cdcfah.com/cp/">產(chǎn)品供應(yīng)</a>?<a href="http://www.cdcfah.com/cp/second-_yyby/">醫(yī)藥健康</a>?<a href="http://www.cdcfah.com/cp/third-yyby_zyfl/">制藥輔料</a>?DL泛解酸內(nèi)酯合成上海臨辰供應(yīng)</p><div id="eol33ei" class="leftbox clearfix"><h1>DL泛解酸內(nèi)酯合成上海臨辰供應(yīng)</h1><div id="tsu7cic" class="proBig"><div id="2gn2i7x" class="bigimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289746210938/9268872.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div><div id="s77htie" class="smallimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289746210938/9268872.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="kzwt9iy" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價(jià)格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>DL泛解酸內(nèi)酯合成</p><p><span>***更新：</span>2020-06-19 00:41:45</p><p><span id="click" >瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="kjbihqx" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海臨辰醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>葉海岑</p><p><span>郵箱: </span>info@linchenpharm.com</p><p><span>電話: </span>13761181955</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span></p><p><span>手機(jī): </span>021-31606595</p><p><span>地址: </span>辰花路5088弄221號(hào)</p><p>[當(dāng)前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="bqipbdk" class="page-proshow02"><p class="title">詳細(xì)說明</p><div id="tnuw477" class="box"><p><p> 化學(xué)法與水解酶拆分法相結(jié)合合成D-泛解酸內(nèi)酯憑借其成熟的工藝。目前在工業(yè)生產(chǎn)中占據(jù)***重要地位。隨著國內(nèi)環(huán)保要求的日益趨嚴(yán)以及產(chǎn)能擴(kuò)大帶來的競爭壓力，DL泛解酸內(nèi)酯合成，升級(jí)D-泛解酸內(nèi)酯的合成工藝勢(shì)在必行。諸多的研究表明，微生物或者酶的應(yīng)用有助于***、綠色地合成高光學(xué)純度的D-泛解酸內(nèi)酯。內(nèi)酯水解酶催化混旋泛解酸內(nèi)酯的選擇性拆分已經(jīng)成功地實(shí)現(xiàn)了工業(yè)生產(chǎn)。 </p> <p> 而羰基還原酶、醇脫氫酶和羥基腈裂合酶等也已在化學(xué)酶法合成D-泛解酸內(nèi)酯方面展現(xiàn)出了巨 </p> <p> 大的應(yīng)用潛力，DL泛解酸內(nèi)酯合成。后續(xù)利用基因工程、蛋白質(zhì)工程以及反應(yīng)工程等技術(shù)，DL泛解酸內(nèi)酯合成，提高酶的表達(dá)量，改善酶的催化性能，優(yōu)化催化反應(yīng)條件，必將進(jìn)一步提升化學(xué)酶法合成D-泛解酸內(nèi)酯的技術(shù)競爭力。 </p> <p> <br /> </p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="DL泛解酸內(nèi)酯合成" src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289746210938/9268872.png"></div><p> 該酶已經(jīng)成功的應(yīng)用于工業(yè)化,取得了很好的綜合效益.為了提高D-泛解酸內(nèi)酯水解酶的酶活力及在低pH條件下的穩(wěn)定性,我們?cè)诨蛩缴蠈?duì)酶進(jìn)行了研究. 利用RT-PCR方法,擴(kuò)增得到了編碼源于串珠鐮孢霉菌(Fusarium moniliforme)CGMCC </p> <p> 0536的D-泛解酸內(nèi)酯水解酶cDNA,對(duì)其結(jié)構(gòu)進(jìn)行分析,根據(jù)分析結(jié)果設(shè)計(jì)了一對(duì)特異引物,成功擴(kuò)增到了編碼D-泛解酸內(nèi)酯水解酶cDNA的結(jié)構(gòu)基因,結(jié)構(gòu)基因同pMD18-T載體連接后,進(jìn)行測(cè)序.D-泛解酸內(nèi)酯水解酶cDNA結(jié)構(gòu)基因序列已在Genebank數(shù)據(jù)庫申請(qǐng)登記,登記號(hào)為AY728018. </p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="DL泛解酸內(nèi)酯合成" src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289625869141/3735503.png"></div><p> 國外D-泛酸鈣、D-泛醇生產(chǎn)公司主要有日本***制藥精細(xì)化學(xué)品公司、德國BASF公司、荷蘭DSM公司等。國外BASF、DSM均采用化學(xué)法生產(chǎn)，而日本***制藥采用生物法酶拆分工藝制備中間體D-泛解酸內(nèi)酯，這也是目前**技術(shù)的工藝。 </p> <p> D-泛酸、D-泛醇是一種重要的維生素***、食品添加劑和飼料添加劑，用途廣、市場(chǎng)需求量很大。世界上主要的泛酸生產(chǎn)廠家有Roche、BASF和日本***制藥。傳統(tǒng)的生產(chǎn)方法是化學(xué)拆分法或鈣鹽誘導(dǎo)結(jié)晶法。化學(xué)拆分的缺點(diǎn)是拆分劑太貴，分離困難，步驟多，成本高，還0性和環(huán)境污染問題。鈣鹽誘導(dǎo)結(jié)晶法步驟多，收率低，投資大，擴(kuò)大生產(chǎn)規(guī)模比較困難。另外，誘導(dǎo)結(jié)晶法不能用于D-泛醇等泛酸衍生物生產(chǎn)。 </p> <p> <br /> </p></p><br /><p>文章來源地址: http://www.cdcfah.com/cp/307766.html</p></div></div></div></div></div><div id="rya8uqs" class="page-right twoColRt"><div id="8ard3ie" class="box01 margin10 clearfix"><h3><a href="http://www.cdcfah.com/cp/">猜你喜歡</a></h3><div id="n33qrie" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/814588.html"><div><img src="http://tyunfile.71360.com/UpLoadFile/2019/11/1/14/637082168864691056_lgpj_5374157.jpg" alt="福建ZF配件哪家強(qiáng) 信息推薦自業(yè)物資供應(yīng)" class="vcenter" 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