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id="lfhoax8" class="container"><ul><li id = "index_index"><a href="http://www.cdcfah.com/"><span>首頁</span></a></li><li id = "index_company"><a ><span>企業(yè)名錄</span></a></li><li id = "index_product"><a href="http://www.cdcfah.com/cp/"><span>產(chǎn)品供應(yīng)</span></a></li><li id = "index_news"><a href="http://www.cdcfah.com/zx/"><span>新聞資訊</span></a></li><li id = "index_article"><a href="http://www.cdcfah.com/xw/"><span>行業(yè)資訊</span></a></li><li id = "index_show"><a href="http://www.cdcfah.com/zh/"><span>展會信息</span></a></li></ul></div></nav><section class="wrap clearfix"><section class="container clearfix tcPro"><section class="home-main container clearfix"><div id="0yt73ul" class="twoCol"><div id="9cjvczd" class="page-proshow clearfix"><p class="current"> 當前位置:<a href="http://www.cdcfah.com/">首頁?<a href="http://www.cdcfah.com/cp/">產(chǎn)品供應(yīng)</a>?<a href="http://www.cdcfah.com/cp/second-_yyby/">醫(yī)藥健康</a>?<a href="http://www.cdcfah.com/cp/third-yyby_zyfl/">制藥輔料</a>?企業(yè)泛解酸內(nèi)酯產(chǎn)品介紹上海臨辰供應(yīng)</p><div id="cr3qheq" class="leftbox clearfix"><h1>企業(yè)泛解酸內(nèi)酯產(chǎn)品介紹上海臨辰供應(yīng)</h1><div id="xrls73w" class="proBig"><div id="tdam2gc" class="bigimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278338760781250/415124.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div><div id="mwoqh2w" class="smallimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278338760781250/415124.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="u7zgn7k" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>企業(yè)泛解酸內(nèi)酯產(chǎn)品介紹</p><p><span>***更新：</span>2020-06-20 04:27:32</p><p><span id="click" >瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="utaceb8" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海臨辰醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>葉海岑</p><p><span>郵箱: </span>info@linchenpharm.com</p><p><span>電話: </span>13761181955</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span></p><p><span>手機: </span>021-31606595</p><p><span>地址: </span>辰花路5088弄221號</p><p>[當前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="0v2v7hz" class="page-proshow02"><p class="title">詳細說明</p><div id="bvnkmt8" class="box"><p><p> 微生物選擇性的不對稱水解DL-泛解酸內(nèi)酯中的D-泛解酸內(nèi)酯，得到D-泛解酸，再將D-泛解酸進行內(nèi)酯化生產(chǎn)D-泛解酸內(nèi)酯。該方法工藝控制簡單，微生物酶專一性好，可以得到高光學(xué)純度的D-泛解酸內(nèi)酯。 </p> <p> <br /> </p> <p> <br /> </p> <p> <br /> </p> <p> 利用D-泛解酸內(nèi)酯水解酶N末端序列,并根據(jù)NCBI中公布的D-泛解酸內(nèi)酯水解酶cDNA序列設(shè)計了一個特異引物，企業(yè)泛解酸內(nèi)酯產(chǎn)品介紹,該引物結(jié)合Oligo(dT)15,以串珠鐮孢霉(Fusarium moniliforme)CGMCC 0536 mRNA反轉(zhuǎn)錄得到的總cDNA為模板進行擴增,獲得約1.5kb左右的片段,將其克隆到T載體上進行測序,對測得的序列進行分析，企業(yè)泛解酸內(nèi)酯產(chǎn)品介紹，企業(yè)泛解酸內(nèi)酯產(chǎn)品介紹,重新設(shè)計了一對引物,并在引物兩端分別加上限制酶EcoRI和SalI的識別位點序列,利用熱啟動PCR成功地擴增出了D-泛解酸內(nèi)酯水解酶基因, </p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="企業(yè)泛解酸內(nèi)酯產(chǎn)品介紹" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278338760781250/415124.png"></div><p style="text-indent:25px">一種高純度的D?泛酸內(nèi)酯的合成方法包括步驟:將DL?泛酸內(nèi)酯加入到水中,在pH為6.0?8.0用酶水解,得到D?泛解酸以及L?泛酸內(nèi)酯;將上述水溶液經(jīng)有機溶劑萃取,得到D?泛解酸的水溶液以及L?泛酸內(nèi)酯有機溶液;將D?泛解酸的水溶液,控溫20?80℃反應(yīng),用酸調(diào)節(jié)pH至1?4,然后關(guān)環(huán)得到D?泛酸內(nèi)酯水溶液;將步驟S3所得的D?泛酸內(nèi)酯水溶液經(jīng)有機溶劑萃取,然后經(jīng)濃縮,蒸餾,結(jié)晶得到D?泛酸內(nèi)酯;將步驟S2所得的L?泛酸內(nèi)酯溶液經(jīng)濃縮、然后在堿性條件下消旋得到DL?泛酸內(nèi)酯。本發(fā)明為泛酸鈣制備得到D?泛酸內(nèi)酯,工藝路線操作簡單,反應(yīng)條件溫和,安全,環(huán)保,原料價廉易得,工業(yè)適應(yīng)性強。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="企業(yè)泛解酸內(nèi)酯產(chǎn)品介紹" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336147089843/7803549.png"></div><p> D-泛酸在生物體內(nèi)的代謝途徑已經(jīng)確定，即經(jīng)α-酮異戊酸，利用酮泛解酸羥甲基轉(zhuǎn)移酶生成酮泛解酸，再利用酮泛解酸還原酶形成泛解酸，***與β-丙氨酸形成D-泛酸。目前，國內(nèi)對維生素B5 的年需求量達2 000 t 以上，而全球年需求量達10 000 t以上 </p> <p> 化學(xué)法合成D-泛解酸內(nèi)酯，從低廉原料出發(fā)經(jīng)多步反應(yīng)合成，工藝成熟，但總體存在化學(xué)條件 </p> <p> 嚴苛、酸堿用量大和能耗較高等問題。生物技術(shù)的發(fā)展為生物酶法合成D-泛解酸內(nèi)酯提供了充分的可行性。目前工業(yè)化合成D-泛解酸內(nèi)酯采用的是化學(xué)法與水解酶拆分法相結(jié)合的技術(shù)路線。 </p> <p> <br /> </p></p><br /><p>文章來源地址: http://www.cdcfah.com/cp/321904.html</p></div></div></div></div></div><div id="qyfheqf" class="page-right twoColRt"><div id="mbtvskv" class="box01 margin10 clearfix"><h3><a href="http://www.cdcfah.com/cp/">猜你喜歡</a></h3><div id="auwduri" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/814588.html"><div><img src="http://tyunfile.71360.com/UpLoadFile/2019/11/1/14/637082168864691056_lgpj_5374157.jpg" alt="福建ZF配件哪家強信息推薦自業(yè)物資供應(yīng)" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></div><p>福建ZF配件哪家強信息推薦自業(yè)物資供應(yīng)</p></a></div><div id="eykcz3k" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/846569.html"><div><img src="https://tyunfile.71360.com/WaterMark/UploadFile/nbzxsw/637298235378037109/764794.png" alt="寧波寧海直接考A2有幾個科目真誠推薦寧波助學(xué)商務(wù)信息咨詢供應(yīng)" 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