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href="http://www.cdcfah.com/cp/second-_yyby/">醫(yī)藥健康</a>?<a href="http://www.cdcfah.com/cp/third-yyby_zyfl/">制藥輔料</a>?l-泛解酸內(nèi)酯等級(jí) 上海臨辰供應(yīng)</p><div id="00gp5at" class="leftbox clearfix"><h1>l-泛解酸內(nèi)酯等級(jí) 上海臨辰供應(yīng)</h1><div id="58eiyrl" class="proBig"><div id="bavzdit" class="bigimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289625869141/3735503.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div><div id="lvuy38q" class="smallimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289625869141/3735503.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="st3yh0r" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價(jià)格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>l-泛解酸內(nèi)酯等級(jí)</p><p><span>***更新：</span>2020-06-24 01:27:42</p><p><span id="click" >瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="53xgkt5" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海臨辰醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>葉海岑</p><p><span>郵箱: </span>info@linchenpharm.com</p><p><span>電話: </span>13761181955</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span></p><p><span>手機(jī): </span>021-31606595</p><p><span>地址: </span>辰花路5088弄221號(hào)</p><p>[當(dāng)前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="zdjygl5" class="page-proshow02"><p class="title">詳細(xì)說明</p><div id="fa3len0" class="box"><p><p style="text-indent:25px">一種微生物新菌株內(nèi)生***HL-02 (PlectospHaereella cucumerina HL-2)及其在微生物轉(zhuǎn)化制備D-泛解酸內(nèi)酯中的應(yīng)用，所述的應(yīng)用以DL-泛解酸內(nèi)酯為底物，以內(nèi)生*** HL-2發(fā)酵所得菌液或菌液制備的初酶液為酶源，20～45℃下，在含有氯化鈣的Tris-HCl緩沖溶液的反應(yīng)體系中進(jìn)行水解反應(yīng)得水解液，l-泛解酸內(nèi)酯等級(jí)，取水解液用乙酸乙酯進(jìn)行酯化反應(yīng)，l-泛解酸內(nèi)酯等級(jí)，反應(yīng)液經(jīng)后處理制得D-泛解酸內(nèi) 酯；本發(fā)明提供了一株新的可產(chǎn)D-泛解酸內(nèi)酯水解酶的微生物菌種內(nèi)生***HL-2，l-泛解酸內(nèi)酯等級(jí)，該菌種應(yīng)用于拆分DL-泛解酸內(nèi)酯，立體選擇性好，反應(yīng)條件溫和。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="l-泛解酸內(nèi)酯等級(jí)" src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289625869141/3735503.png"></div><p> D-泛解酸內(nèi)酯水解酶活性篩選系統(tǒng).用該篩選系統(tǒng)以酶活力和pH穩(wěn)定性為指標(biāo)對(duì)突變體庫進(jìn)行篩選,**終獲得一株酶活力高且在低pH條件下穩(wěn)定性好的突變體Mut E-861.該突變體的酶活力是野生型酶的5.5倍.對(duì)突變體和野生型酶在pH </p> <p> 6.0和pH 5.0條件下的殘余酶活進(jìn)行對(duì)比,在這兩種pH條件下,突變體酶的酶活殘留分別為75%和50%,而野生型酶只能保持原來的40%和20%.通過軟件對(duì)突變體Mut E-861酶基因和野生型酶基因進(jìn)行分析對(duì)比,發(fā)現(xiàn)突變體Mut E-861酶基因發(fā)生了三處點(diǎn)突變,其中突變使兩處氨基酸取代,另一處為沉默突變,未引起氨基酸的變化. </p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="l-泛解酸內(nèi)酯等級(jí)" src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289746210938/9268872.png"></div><p style="text-indent:25px">維生素B5（VitaminB5）又稱D-維生素B5，是人體必需的13種維生素之一，是一種水溶性維生素，維生素B族成員之一，是它是輔酶a（CoA）及?；d體蛋白（acylcarrierprotein,acp）的組成部分。機(jī)體內(nèi)的泛酸，幾乎都用以組成輔酶a及acp的輔基。VB5前段生產(chǎn)工藝有多種，生產(chǎn)后段拆分方法有化學(xué)和微生物酶拆法兩種。VB5（D-維生素B5）首先要制備2個(gè)重要的中間體，分別為β-氨基丙酸和DL-泛解酸內(nèi)酯。β-氨基丙酸的合成有丙烯腈路線、丙烯酸路線、琥珀酰亞胺路線等，現(xiàn)國內(nèi)生產(chǎn)廠大多采用丙烯腈路線。</p></p><br /><p>文章來源地址: http://www.cdcfah.com/cp/368756.html</p></div></div></div></div></div><div id="ng13usu" class="page-right twoColRt"><div id="pkpyrlt" class="box01 margin10 clearfix"><h3><a href="http://www.cdcfah.com/cp/">猜你喜歡</a></h3><div id="or185ge" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/814588.html"><div><img src="http://tyunfile.71360.com/UpLoadFile/2019/11/1/14/637082168864691056_lgpj_5374157.jpg" alt="福建ZF配件哪家強(qiáng) 信息推薦自業(yè)物資供應(yīng)" class="vcenter" 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