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href="http://www.cdcfah.com/cp/">產(chǎn)品供應</a>?<a href="http://www.cdcfah.com/cp/second-_yyby/">醫(yī)藥健康</a>?<a href="http://www.cdcfah.com/cp/third-yyby_zyfl/">制藥輔料</a>?**泛解酸內酯推薦上海臨辰供應</p><div id="k4ykoso" class="leftbox clearfix"><h1>**泛解酸內酯推薦上海臨辰供應</h1><div id="f0cbgnu" class="proBig"><div id="zqx34kr" class="bigimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336219531250/8019769.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div><div id="hypyplc" class="smallimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336219531250/8019769.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="frovmtv" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關鍵詞：</span>**泛解酸內酯推薦</p><p><span>***更新：</span>2020-06-27 13:23:32</p><p><span id="click" >瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="u8zg3ok" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海臨辰醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>葉海岑</p><p><span>郵箱: </span>info@linchenpharm.com</p><p><span>電話: </span>13761181955</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span></p><p><span>手機: </span>021-31606595</p><p><span>地址: </span>辰花路5088弄221號</p><p>[當前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="dulxzf2" class="page-proshow02"><p class="title">詳細說明</p><div id="onpwyfe" class="box"><p><p> D-泛解酸內酯水解酶活性篩選系統(tǒng).用該篩選系統(tǒng)以酶活力和pH穩(wěn)定性為指標對突變體庫進行篩選,**終獲得一株酶活力高且在低pH條件下穩(wěn)定性好的突變體Mut E-861，**泛解酸內酯推薦.該突變體的酶活力是野生型酶的5.5倍.對突變體和野生型酶在pH </p> <p> 6.0和pH 5.0條件下的殘余酶活進行對比,在這兩種pH條件下,突變體酶的酶活殘留分別為75%和50%，**泛解酸內酯推薦,而野生型酶只能保持原來的40%和20%.通過軟件對突變體Mut E-861酶基因和野生型酶基因進行分析對比，**泛解酸內酯推薦,發(fā)現(xiàn)突變體Mut E-861酶基因發(fā)生了三處點突變,其中突變使兩處氨基酸取代,另一處為沉默突變,未引起氨基酸的變化. </p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="**泛解酸內酯推薦" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336219531250/8019769.png"></div><p style="text-indent:25px">KATAOKA M 等于1992 年分離純化出星狀諾卡氏菌生產(chǎn)的L-泛解酸內酯脫氫酶，但比酶活只有0.041 7 U/mg。該菌的基因組信息已被披露，然而至今未有構建其L-泛解酸內酯脫氫酶基因工程菌的報道。2009 年，王永澤等利用面包酵母生產(chǎn)酮泛解酸內酯還原酶，并利用β-環(huán)糊精結合底物，減少底物對菌體的0作用，終產(chǎn)物得率達45%，光學純度達到90%以上。SI D等于2012 年在嗜麥芽寡養(yǎng)單孢菌845 中克隆一個大小約為30 kDa 的酮泛解酸還原酶，并與葡萄糖脫氫酶共表達成大腸工程菌，構建輔酶循環(huán)體系。該大腸工程菌的酮泛解酸還原酶的比酶活達到27.7 U/mg。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="**泛解酸內酯推薦" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336263828125/6823745.png"></div><p> 傳統(tǒng)的生產(chǎn)方法是化學拆分法或鈣鹽誘導結晶法?；瘜W拆分的缺點是拆分劑太貴，分離困難，步驟多，成本高，還0性和環(huán)境污染問題。鈣鹽誘導結晶法步驟多，收率低，投資大，擴大生產(chǎn)規(guī)模比較困難。另外，誘導結晶法不能用于D－泛醇等泛酸衍生物生產(chǎn)。 </p> <p> “微生物酶法拆分制備D－泛解酸內酯及用于生產(chǎn)D－泛酸鈣與D－泛醇”項目選育了一株能高產(chǎn)立體專一性D－泛解酸內酯水解酶、不利用不降解泛解酸內酯或泛解酸的微生物菌株串珠鐮孢霉，建立了國際**的霉菌交聯(lián)原位固定化方法，酶轉化時間短到3～5小時，效率高，反復分批酶轉化可達180次以上，所得到的酶水解產(chǎn)物光學純度達到99％e．e．以上，因此具有較好的技術經(jīng)濟競爭力。 </p></p><br /><p>文章來源地址: http://www.cdcfah.com/cp/411594.html</p></div></div></div></div></div><div id="pe24jp8" class="page-right twoColRt"><div id="ogsebsw" class="box01 margin10 clearfix"><h3><a href="http://www.cdcfah.com/cp/">猜你喜歡</a></h3><div id="k7evmdu" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/814588.html"><div><img src="http://tyunfile.71360.com/UpLoadFile/2019/11/1/14/637082168864691056_lgpj_5374157.jpg" alt="福建ZF配件哪家強信息推薦自業(yè)物資供應" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></div><p>福建ZF配件哪家強信息推薦自業(yè)物資供應</p></a></div><div id="x3mjace" 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