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src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336147089843/7803549.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div><div id="ixwy39x" class="smallimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336147089843/7803549.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="3b99yb8" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>高純度泛解酸內(nèi)酯承諾守信</p><p><span>***更新：</span>2020-06-28 16:31:11</p><p><span id="click" >瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="7dcoso4" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海臨辰醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>葉海岑</p><p><span>郵箱: </span>info@linchenpharm.com</p><p><span>電話: </span>13761181955</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span></p><p><span>手機(jī): </span>021-31606595</p><p><span>地址: </span>辰花路5088弄221號</p><p>[當(dāng)前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="vzmov8b" class="page-proshow02"><p class="title">詳細(xì)說明</p><div id="8k4bfml" class="box"><p><p> 化還原酶催化不對稱還原制備D-泛解酸內(nèi)酯氧化還原酶不對稱還原酮泛解酸內(nèi)酯的方法。用L-泛解酸內(nèi)酯脫氫酶將L-泛解酸內(nèi)酯氧化成酮泛解酸內(nèi)酯，再利用酮泛解酸內(nèi)酯還原酶將其不對稱還原成D-泛解酸內(nèi)酯。該方法也可將外消旋的泛解酸內(nèi)酯作為起始原料，經(jīng)過氧化還原反應(yīng)后得到D-泛解酸內(nèi)酯，高純度泛解酸內(nèi)酯承諾守信，高純度泛解酸內(nèi)酯承諾守信，過程簡單，不需要化學(xué)法中的再消旋化反應(yīng)。 </p> <p> <p> 制備方法包括以下步驟：(1)將纈氨酸在過氧化氫酶和α?酮異戊酸還原酶的作用下，進(jìn)行酶轉(zhuǎn)化得到α?酮異戊酸； </p> <p> <br /> </p> <p> (2)將所述α?酮異戊酸與四氫葉酸在羥甲基轉(zhuǎn)移酶和氯化鎂的作用下，高純度泛解酸內(nèi)酯承諾守信，反應(yīng)制備酮泛解酸； </p> <p> <br /> </p> <p> (3)將所述酮泛解酸在α?酮異戊酸還原酶的作用下，進(jìn)行酶轉(zhuǎn)化得到泛解酸； </p> <p> <br /> </p> <p> (4)將所述泛解酸制備得到泛解酸內(nèi)酯。 </p> </p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="高純度泛解酸內(nèi)酯承諾守信" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336147089843/7803549.png"></div><p> D-泛酸鈣，化學(xué)名為N-(α,γ-二羥基-β,β-二甲基丁酰)-β-氨基丙酸鈣，俗稱維生素B5，是輔酶A的組成部分，它是人體和動物維持正常生理機(jī)能不可缺少的物質(zhì)，廣泛應(yīng)用于飼料、醫(yī)藥、食品等工業(yè)。 </p> <p> D-泛醇，俗稱維生素原B5，是一種優(yōu)異的皮膚與頭發(fā)保護(hù)劑，可使皮膚保持柔嫩、毛發(fā)光亮油潤，廣泛應(yīng)用在護(hù)發(fā)產(chǎn)品和化妝品中，還可用于醫(yī)藥、保健食品等領(lǐng)域。 </p> <p> D-泛酸鈣的制備方法主要有以下兩種。 </p> <p> 一種是先化學(xué)合成DL-泛酸鈣，通過拆分DL-泛酸鈣而制得D-泛酸鈣。 </p> <p> 另一種是通過化學(xué)法或生物法拆分關(guān)鍵中間體DL-泛解酸內(nèi)酯得到D-泛解酸內(nèi)酯，再由D-泛解酸內(nèi)酯與β--氨基丙酸反應(yīng)合成D-泛酸鈣。 </p> <p> D-泛醇由D-泛解酸內(nèi)酯與β--氨基丙醇反應(yīng)制得。 </p> <p> <br /> </p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="高純度泛解酸內(nèi)酯承諾守信" src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289561562500/2636284.png"></div><p style="text-indent:25px">一種ＤＬ－泛酰內(nèi)酯的拆分方法?，F(xiàn)有拆分方法中使用的拆分劑在拆分ＤＬ－泛酰內(nèi)酯時的選擇性低，使ＤＬ－泛酰內(nèi)酯的總利用率低，提高了拆分ＤＬ－泛酰內(nèi)酯的生產(chǎn)成本。本發(fā)明所用的拆分劑為有機(jī)堿Ｒ－ＮＨ＃－［２］，其中Ｒ為Ｃ＃－［１５］Ｈ＃－［１５］，包括以下步驟：ａ）用純化后的拆分劑與酸反應(yīng)，加水、加熱溶解，滴加ＤＬ－泛酰內(nèi)酯水解液，拆分劑：ＤＬ－泛酰內(nèi)酯的摩爾比＝０．５－０．７∶１；ｂ）抽濾由ａ得到的反應(yīng)液，濾餅進(jìn)行消旋、回收拆分劑處理，濾液加入有機(jī)溶劑進(jìn)行共沸脫水，蒸去過量有機(jī)溶劑進(jìn)行結(jié)晶。本發(fā)明明顯提高了拆分劑對Ｄ－泛酰內(nèi)酯的選擇性，提高ＤＬ－泛酰內(nèi)酯的總利用率，拆分收率高，減少拆分劑的用量且容易重復(fù)回收利用，降低拆分ＤＬ－泛酰內(nèi)酯的生產(chǎn)成本。</p></p><br /><p>文章來源地址: http://www.cdcfah.com/cp/425507.html</p></div></div></div></div></div><div id="jylik7h" class="page-right twoColRt"><div id="bqn8daz" class="box01 margin10 clearfix"><h3><a href="http://www.cdcfah.com/cp/">猜你喜歡</a></h3><div id="lac9kmt" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/814588.html"><div><img src="http://tyunfile.71360.com/UpLoadFile/2019/11/1/14/637082168864691056_lgpj_5374157.jpg" alt="福建ZF配件哪家強(qiáng) 信息推薦自業(yè)物資供應(yīng)" class="vcenter" 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