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onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div><div id="8gpxy3s" class="smallimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289625869141/3735503.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="obggqup" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>**泛解酸內(nèi)酯型號</p><p><span>***更新：</span>2020-06-29 16:33:19</p><p><span id="click" >瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="ybxyeap" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海臨辰醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>葉海岑</p><p><span>郵箱: </span>info@linchenpharm.com</p><p><span>電話: </span>13761181955</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span></p><p><span>手機: </span>021-31606595</p><p><span>地址: </span>辰花路5088弄221號</p><p>[當(dāng)前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="trsc2nn" class="page-proshow02"><p class="title">詳細(xì)說明</p><div id="kx3fwbl" class="box"><p><p> 傳統(tǒng)的生產(chǎn)方法是化學(xué)拆分法或鈣鹽誘導(dǎo)結(jié)晶法?；瘜W(xué)拆分的缺點是拆分劑太貴，分離困難，步驟多，成本高，**泛解酸內(nèi)酯型號，還0性和環(huán)境污染問題。鈣鹽誘導(dǎo)結(jié)晶法步驟多，收率低，投資大，擴大生產(chǎn)規(guī)模比較困難。另外，誘導(dǎo)結(jié)晶法不能用于D－泛醇等泛酸衍生物生產(chǎn)。 </p> <p> “微生物酶法拆分制備D－泛解酸內(nèi)酯及用于生產(chǎn)D－泛酸鈣與D－泛醇”項目選育了一株能高產(chǎn)立體專一性D－泛解酸內(nèi)酯水解酶、不利用不降解泛解酸內(nèi)酯或泛解酸的微生物菌株串珠鐮孢霉，**泛解酸內(nèi)酯型號，建立了國際**的霉菌交聯(lián)原位固定化方法，**泛解酸內(nèi)酯型號，酶轉(zhuǎn)化時間短到3～5小時，效率高，反復(fù)分批酶轉(zhuǎn)化可達180次以上，所得到的酶水解產(chǎn)物光學(xué)純度達到99％e．e．以上，因此具有較好的技術(shù)經(jīng)濟競爭力。 </p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="**泛解酸內(nèi)酯型號" src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289625869141/3735503.png"></div><p style="text-indent:25px">泛酸鈣在臨床上主要用于泛酸鈣缺乏的預(yù)防和***，如吸收不良綜合征、熱帶口炎性腹瀉、乳糜瀉、局限性腸炎或應(yīng)用泛酸鈣拮抗***的時候。另外用于一些其他疾病的輔助***如鏈霉素中毒、術(shù)后腸梗阻、類風(fēng)濕等等。還用于維生素B缺乏癥以及周圍神經(jīng)炎、手術(shù)后腸絞痛，另外口角炎也可以用泛酸鈣。一般情況下，此藥沒有什么不良反應(yīng)，但是對于有一些人群對泛酸鈣過敏的是不能用的。另外患了血友病的病人也是不能服用，因為會延長患者的出血時間，對于這些癥狀的病人，在臨床上要慎用。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="**泛解酸內(nèi)酯型號" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336299169921/7145872.png"></div><p style="text-indent:25px">一種高純度的D?泛酸內(nèi)酯的合成方法包括步驟:將DL?泛酸內(nèi)酯加入到水中,在pH為6.0?8.0用酶水解,得到D?泛解酸以及L?泛酸內(nèi)酯;將上述水溶液經(jīng)有機溶劑萃取,得到D?泛解酸的水溶液以及L?泛酸內(nèi)酯有機溶液;將D?泛解酸的水溶液,控溫20?80℃反應(yīng),用酸調(diào)節(jié)pH至1?4,然后關(guān)環(huán)得到D?泛酸內(nèi)酯水溶液;將步驟S3所得的D?泛酸內(nèi)酯水溶液經(jīng)有機溶劑萃取,然后經(jīng)濃縮,蒸餾,結(jié)晶得到D?泛酸內(nèi)酯;將步驟S2所得的L?泛酸內(nèi)酯溶液經(jīng)濃縮、然后在堿性條件下消旋得到DL?泛酸內(nèi)酯。本發(fā)明為泛酸鈣制備得到D?泛酸內(nèi)酯,工藝路線操作簡單,反應(yīng)條件溫和,安全,環(huán)保,原料價廉易得,工業(yè)適應(yīng)性強。</p></p><br /><p>文章來源地址: 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