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onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div><div id="hliapg7" class="smallimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336299169921/7145872.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="en873b7" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>D-泛醇泛解酸內(nèi)酯推薦,泛解酸內(nèi)酯</p><p><span>***更新：</span>2020-07-02 14:21:53</p><p><span id="click" >瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="zt2hlxw" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海臨辰醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>葉海岑</p><p><span>郵箱: </span>info@linchenpharm.com</p><p><span>電話: </span>13761181955</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span></p><p><span>手機(jī): </span>021-31606595</p><p><span>地址: </span>辰花路5088弄221號</p><p>[當(dāng)前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="7ebiugx" class="page-proshow02"><p class="title">詳細(xì)說明</p><div id="ixjvcel" class="box"><p><p> D-泛解酸內(nèi)酯包裝:25kg紙板桶。 </p> <p> <br /> </p> <p> 性狀：白色或類白色結(jié)晶性粉末，本品溶解性：易溶于水，D-泛醇泛解酸內(nèi)酯推薦，溶于乙醇、***、氯仿。 </p> <p> <br /> </p> <p> 合成維生素B5即D-泛酸鈣主要原料，目前采用化學(xué)合成DL-泛解酸內(nèi)酯，D-泛醇泛解酸內(nèi)酯推薦，再經(jīng)過生物拆分得到。 </p> <p> <br /> </p> <p> D-泛解酸內(nèi)酯是一種重要的原料藥中間體。 </p> <p> <br /> </p> <p> D-泛解酸內(nèi)酯主要用于D-泛酸鈣和D-泛醇的合成。 </p> <p> <br /> </p> <p> D?泛解酸內(nèi)酯的制備方法，D-泛醇泛解酸內(nèi)酯推薦。 </p> <p> <br /> </p> <p> 制備方法包括以下步驟：(1)將纈氨酸在過氧化氫酶和α?酮異戊酸還原酶的作用下，進(jìn)行酶轉(zhuǎn)化得到α?酮異戊酸； </p> <p> <br /> </p> <p> (2)將所述α?酮異戊酸與四氫葉酸在羥甲基轉(zhuǎn)移酶和氯化鎂的作用下，反應(yīng)制備酮泛解酸； </p> <p> <br /> </p> <p> (3)將所述酮泛解酸在α?酮異戊酸還原酶的作用下，進(jìn)行酶轉(zhuǎn)化得到泛解酸； </p> <p> <br /> </p> <p> (4)將所述泛解酸制備得到泛解酸內(nèi)酯。婦孕嬰兒的食品中一般均添加泛酸。D-泛醇泛解酸內(nèi)酯推薦</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="D-泛醇泛解酸內(nèi)酯推薦,泛解酸內(nèi)酯" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336299169921/7145872.png"></div><p> (S)-(+)-泛解酸內(nèi)酯（L-Pantolactone），分子式為C6H10O3。 </p> <p> 中文名稱 </p> <p> (S)-(+)-泛解酸內(nèi)酯英文名稱 </p> <p> L-Pantolactone中文別名 </p> <p> L-(+)-泛解酸內(nèi)酯;S-泛解酸內(nèi)酯;英文別名 </p> <p> (3S)-3-hydroxy-4,4-dimethyloxolan-2-one;(S)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one;L-(+)-Pantolactone;CAS號 </p> <p> 5405-40-3 分子式 </p> <p> C6H10O3分子量 </p> <p> 130.14200精確質(zhì)量 </p> <p> 130.06300PSA </p> <p> 46.53000LogP </p> <p> -0.06970 </p> <p> <p> 物化性質(zhì)折射率：1.469 </p> <p> 閃點：99oC </p> <p> 熔點：90-94oC </p> <p> 密度：1.165g/cm3 </p> <p> 沸點：120-122oC/15mmHg(lit.)。 </p> 穩(wěn)定供應(yīng)泛解酸內(nèi)酯服務(wù)商中文別名:D-(-)-Pantolactone D-(-)-泛酰內(nèi)酯。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="D-泛醇泛解酸內(nèi)酯推薦,泛解酸內(nèi)酯" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336180390625/6214460.png"></div><p style="text-indent:25px">選擇6種吸附樹脂和離子交換樹脂對D-泛解酸內(nèi)酯水解酶進(jìn)行固定化,篩選出了固定化效果較好的大孔弱堿性丙烯酸系陰離子交換樹脂D-380為載體,用先吸附后交聯(lián)的方法固定化。通過實驗對固定化條件進(jìn)行了優(yōu)化,得出比較好的固定化條件為:加酶量6 U/g樹脂、吸附pH 7.5、吸附時間4 h、吸附溫度30℃、交聯(lián)劑戊二醛終濃度0.1%、交聯(lián)時間2 h。實驗表明在此條件下制得的固定化酶有很好的穩(wěn)定性:固定化酶在連續(xù)20次的底物水解反應(yīng)后,剩余酶活達(dá)到71%。當(dāng)溫度達(dá)到80℃時游離酶幾乎失去酶活,而固定化酶剩余酶活為60%以上。游離酶的pH穩(wěn)定性范圍為pH 7～8,而固定化酶為pH 6.5～8.5。</p><p> 生產(chǎn)工藝為：D-泛解酸鈉溶液 –內(nèi)酯化，得到D-泛解酸內(nèi)酯溶液-溶液減壓濃縮脫除水分-結(jié)晶-固液分離，母液回套至減壓濃縮脫水-D-泛解酸內(nèi)酯成品-β-丙氨酸、氧化鈣、甲醇進(jìn)行鈣化反應(yīng)，生成β-丙氨酸鈣-加入甲醇、D-泛解酸內(nèi)酯進(jìn)行?；磻?yīng)，生成D-泛酸鈣-結(jié)晶、離心- D-泛酸鈣濕粉干燥-整粒、包裝入庫。 </p> <p> <br /> </p> <p> 一種高純度的D?泛酸內(nèi)酯的合成方法包括步驟:將DL?泛酸內(nèi)酯加入到水中,在pH為6.0?8.0用酶水解,得到D?泛解酸以及L?泛酸內(nèi)酯;將上述水溶液經(jīng)有機(jī)溶劑萃取,得到D?泛解酸的水溶液以及L?泛酸內(nèi)酯有機(jī)溶液。 D-泛解酸內(nèi)酯CAS號599-04-2。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="D-泛醇泛解酸內(nèi)酯推薦,泛解酸內(nèi)酯" src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289625869141/3735503.png"></div><p style="text-indent:25px">羥基腈裂合酶催化不對稱合成D-泛解酸內(nèi)酯前體(R)-氰醇(R)-氰醇是D-泛解酸內(nèi)酯的前體物質(zhì)，可經(jīng)過水解生產(chǎn)D-泛解酸內(nèi)酯。利用(R)-羥基腈裂合酶催化HCN 與羥基特戊醛的羰基碳不對稱加成進(jìn)而合成(R)-氰醇。大多數(shù)參與醇腈化反應(yīng)的酶主要存在于高等植物中，例如巴旦杏、蘋果、薔薇、橡膠樹、亞麻類等，在植物體內(nèi)羥基腈裂解酶催化形成氫腈酸從而抵御外來物種的入侵。2007 年荷蘭DSM 公司從巴旦杏中提取分離的(R)-羥基腈裂合酶能選擇性合成(R)-氰醇，并構(gòu)建了粟酒裂殖酵母工程菌。2014 年，DSM 公司將來自薔薇科的(R)-羥基腈裂合酶基因構(gòu)建于pJET 重組質(zhì)粒，并導(dǎo)入巴斯德酵母中表達(dá)，確定了該重組酶**適條件范圍為15~20 ℃以及pH 2.5~3.0。在15 ℃和pH 2.5 下醇腈化反應(yīng)2 d，反應(yīng)收率達(dá)到93%，轉(zhuǎn)化率達(dá)**，產(chǎn)物光學(xué)純度達(dá)92%。D-泛解酸內(nèi)酯被D-泛解酸內(nèi)酯水解酶水解成酸性的D-泛解酸。高純泛解酸內(nèi)酯廠家供應(yīng)</p><p style="text-indent:25px">D-泛解酸內(nèi)酯分子式 C6H10O3 。D-泛醇泛解酸內(nèi)酯推薦</p><p> 化還原酶催化不對稱還原制備D-泛解酸內(nèi)酯氧化還原酶不對稱還原酮泛解酸內(nèi)酯的方法。用L-泛解酸內(nèi)酯脫氫酶將L-泛解酸內(nèi)酯氧化成酮泛解酸內(nèi)酯，再利用酮泛解酸內(nèi)酯還原酶將其不對稱還原成D-泛解酸內(nèi)酯。該方法也可將外消旋的泛解酸內(nèi)酯作為起始原料，經(jīng)過氧化還原反應(yīng)后得到D-泛解酸內(nèi)酯，過程簡單，不需要化學(xué)法中的再消旋化反應(yīng)。 </p> <p> <p> 制備方法包括以下步驟：(1)將纈氨酸在過氧化氫酶和α?酮異戊酸還原酶的作用下，進(jìn)行酶轉(zhuǎn)化得到α?酮異戊酸； </p> <p> <br /> </p> <p> (2)將所述α?酮異戊酸與四氫葉酸在羥甲基轉(zhuǎn)移酶和氯化鎂的作用下，反應(yīng)制備酮泛解酸； </p> <p> <br /> </p> <p> (3)將所述酮泛解酸在α?酮異戊酸還原酶的作用下，進(jìn)行酶轉(zhuǎn)化得到泛解酸； </p> <p> <br /> </p> <p> (4)將所述泛解酸制備得到泛解酸內(nèi)酯。 </p> D-泛醇泛解酸內(nèi)酯推薦</p><p style="text-indent:25px">上海臨辰醫(yī)藥科技有限公司始建于2016-04-05，坐落于辰花路5088弄221號，現(xiàn)有員工5~10人余人。Domanchem,多曼,NEXIRA,Ashland,BASF,Evonik,ROQUETTE,DFE,JBCOCO,JRS,BENOE,GIFU,StrahlPitsch,CYCLOLAB,SDFine,Avantor,Sudeep,Ambuja,Animo,kyowa-chem,caps-roxlor,MSI,CABOT,Danisco,DoPant,Sasol,Seppic,Clariant,Solvay,EASTMAN,DSM,Pfanstiehl,ANGUS,Cargill,Hopax,IMERYS,KEONOS,KIMICA,LYSI,MERCK,SABINSA,Vertellus,Watson是上海臨辰醫(yī)藥科技有限公司的主營品牌，是專業(yè)的Plasdone?聚維酮(PVP)，Polyplasdone?交聯(lián)聚維酮(PVPP)，Plasdone?共聚維酮（PVP/VA)，Benecel?羥丙甲纖維素(HPMC)，Klucel?羥丙纖維素(HPC) 硬脂富馬酸鈉，羧甲基淀粉鈉，交聯(lián)羧甲基纖維素鈉，微晶纖維素，磷酸氫鈣（無水/二水）USP-NF,Ph.Eur,JP" D-(+)-半乳糖（植物）蔗糖，異麥芽糖，異麥芽酮糖醇，三氯蔗糖，環(huán)氨酸鈉（甜蜜素)，赤蘚糖醇丁香酚，丁香油，蓖麻油，芝麻油，橄欖油，中鏈甘油三酸酯，乙酰單酸甘油乙酯，蔗糖脂肪酸酯聚乙二醇3350/1000/4000/6000/8000，白陶土，液體石蠟，輕質(zhì)液體石蠟，（干燥）氫氧化鋁凝膠，薄荷腦，合成鋁碳酸鎂，合成硅酸鋁，氧化鎂，氫氧化鎂，甘羥鋁，甘氨酸鋁，磷酸鈣（二水/無水），三硅酸鎂，滑石粉，BHA,BHT,多庫酯鈉，組氨酸，鹽酸組氨酸，精氨酸，鹽酸精氨酸，絲氨酸，半胱氨酸，丙氨酸， Pfanstiehl海藻糖（二水），蔗糖（甘蔗/甜菜），甘露醇，精氨酸，琥珀酸二鈉（無水），氨丁三醇 (含低內(nèi)*素），活性炭（供注射）色素系列黃/紅氧化鐵，檸檬黃色淀，公司，擁有自己**的技術(shù)體系。公司堅持以客戶為中心、Plasdone?聚維酮(PVP)，Polyplasdone?交聯(lián)聚維酮(PVPP)，Plasdone?共聚維酮（PVP/VA)，Benecel?羥丙甲纖維素(HPMC)，Klucel?羥丙纖維素(HPC) 硬脂富馬酸鈉，羧甲基淀粉鈉，交聯(lián)羧甲基纖維素鈉，微晶纖維素，磷酸氫鈣（無水/二水）USP-NF,Ph.Eur,JP" D-(+)-半乳糖（植物）蔗糖，異麥芽糖，異麥芽酮糖醇，三氯蔗糖，環(huán)氨酸鈉（甜蜜素)，赤蘚糖醇丁香酚，丁香油，蓖麻油，芝麻油，橄欖油，中鏈甘油三酸酯，乙酰單酸甘油乙酯，蔗糖脂肪酸酯聚乙二醇3350/1000/4000/6000/8000，白陶土，液體石蠟，輕質(zhì)液體石蠟，（干燥）氫氧化鋁凝膠，薄荷腦，合成鋁碳酸鎂，合成硅酸鋁，氧化鎂，氫氧化鎂，甘羥鋁，甘氨酸鋁，磷酸鈣（二水/無水），三硅酸鎂，滑石粉，BHA,BHT,多庫酯鈉，組氨酸，鹽酸組氨酸，精氨酸，鹽酸精氨酸，絲氨酸，半胱氨酸，丙氨酸， Pfanstiehl海藻糖（二水），蔗糖（甘蔗/甜菜），甘露醇，精氨酸，琥珀酸二鈉（無水），氨丁三醇 (含低內(nèi)*素），活性炭（供注射）色素系列黃/紅氧化鐵，檸檬黃色淀，市場為導(dǎo)向，重信譽(yù)，保質(zhì)量，想客戶之所想，急用戶之所急，全力以赴滿足客戶的一切需要。上海臨辰醫(yī)藥科技有限公司主營業(yè)務(wù)涵蓋[ "泛解酸內(nèi)酯", "有機(jī)可可粉有機(jī)果粉", "阿拉伯膠瓜爾膠 ", "BIS TRIS " ]，堅持“質(zhì)量***、質(zhì)量服務(wù)、顧客滿意”的質(zhì)量方針，贏得廣大客戶的支持和信賴。</p></p><br /><p>文章來源地址: http://www.cdcfah.com/cp/470538.html</p></div></div></div></div></div><div id="fxelnuw" class="page-right twoColRt"><div id="nxurtam" class="box01 margin10 clearfix"><h3><a 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