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>瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="c3a3k3c" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海臨辰醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>葉海岑</p><p><span>郵箱: </span>info@linchenpharm.com</p><p><span>電話: </span>13761181955</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span></p><p><span>手機(jī): </span>021-31606595</p><p><span>地址: </span>辰花路5088弄221號(hào)</p><p>[當(dāng)前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="nzqnp2m" class="page-proshow02"><p class="title">詳細(xì)說明</p><div id="tn8xutu" class="box"><p><p> D-泛解酸內(nèi)酯的傳統(tǒng)工業(yè)方法是化學(xué)拆分法和生物拆分法。 </p> <p> <br /> </p> <p> 這兩種方法生產(chǎn)過程復(fù)雜，拆分試劑制備回收繁瑣，生產(chǎn)成本高。 </p> <p> <br /> </p> <p> 探求其新的拆分方法，完善生產(chǎn)工藝，提高產(chǎn)品質(zhì)量，一直成為研究者和生產(chǎn)者追求的目的。 </p> <p> <br /> </p> <p> 實(shí)質(zhì)上在拆分工藝的三種傳統(tǒng)方法中（化學(xué)拆分，大量供應(yīng)泛解酸內(nèi)酯599-04-2、生物拆分、誘導(dǎo)拆分）。 </p> <p> <br /> </p> <p> 生產(chǎn)D-泛酸鈣進(jìn)行了幾十年的摸索，先后采用了誘導(dǎo)拆分DL-泛酸鈣法、化學(xué)拆分D-泛解酸內(nèi)酯法和生物拆分法，大量供應(yīng)泛解酸內(nèi)酯599-04-2。 </p> <p> <br /> </p> <p> 生產(chǎn)D-泛酸鈣，大量供應(yīng)泛解酸內(nèi)酯599-04-2，近年來拆分方法基本上統(tǒng)一到了生物拆分制備法。婦孕嬰兒的食品中一般均添加泛酸。大量供應(yīng)泛解酸內(nèi)酯599-04-2</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="大量供應(yīng)泛解酸內(nèi)酯599-04-2,泛解酸內(nèi)酯" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336180390625/6214460.png"></div><p style="text-indent:25px">CAS: 137-08-6分子式: C18H32CaN2O10分子量: 476.54中文名稱: 右旋泛酸鈣(R)-N-(2,4-二羥基-3,3-二甲基-1-氧代丁基)-β-丙氨酸鈣(2:1)D-泛酸鈣泛酸鈣本多生酸鈣N-(2,4-二羥基-3,3-二甲基丁酰)-β-氨基丙酸鈣維生素B5標(biāo)準(zhǔn)品英文名稱: Calcium D-pantothenateN-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1), (R)-.beta.-AlaninePantholincalcium salt (2:1), (+)-pantothenic acibeta-alanine, n-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1),( theta)-(+)-pantothenic acid calcium saltcalcium d(+)-n-(alpha,gamma-dihydroxy-beta,beta-dimethylbutyryl)-beta-alaninacalcium panthothenatecalcium pantothenatecalpanated-calcium pantothenatedextro calcium pantothenaten-(2,4-dihydroxy-3,3-dimethylbutyryl)-beta-alanine calciumD-泛解酸內(nèi)酯承諾守信從近十年的年消費(fèi)量分析，D-泛醇其年消費(fèi)增長率在10%以上。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="大量供應(yīng)泛解酸內(nèi)酯599-04-2,泛解酸內(nèi)酯" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336263828125/6823745.png"></div><p style="text-indent:25px">D-泛解酸內(nèi)酯?，F(xiàn)有技術(shù)中還有在培養(yǎng)基中培養(yǎng)尖孢鐮孢菌，在培養(yǎng)后的尖孢鐮孢菌與底物混合，水解得到D-泛解酸，內(nèi)酯化獲得D-泛解酸內(nèi)酯，但是本方法采用發(fā)酵制備D-泛解酸內(nèi)酯的過程能耗較高，且產(chǎn)率低，工業(yè)成本較高。現(xiàn)有技術(shù)中還有以水和甲苯為溶劑體系，通過添加D-泛解酸內(nèi)酯作為晶種，誘導(dǎo)結(jié)晶獲得D-泛解酸內(nèi)酯的方法，但是本方法在生產(chǎn)過程中采用了甲苯，生產(chǎn)過程VOC排放較高，且通過誘導(dǎo)結(jié)晶獲得的一次收率較低，產(chǎn)品比旋度較低。</p><p style="text-indent:25px">早在1973 年，KING H L 等就研究發(fā)現(xiàn)一種來源于釀酒酵母的NADP（H）依賴型的酮泛解酸還原酶能夠?qū)⑼航馑徇€原為D-泛解酸內(nèi)酯，該酶在pH 7.0 條件下需要2.2 min 反應(yīng)延滯期才會(huì)催化酮泛解酸內(nèi)酯形成D-泛解酸內(nèi)酯。1984 年，日本學(xué)者SHIMIZU S 等篩選了一系列能夠還原酮泛解酸內(nèi)酯形成泛解酸內(nèi)酯的微生物菌種，其中小紅酵母、不對稱擲孢酵母、**滑假絲酵母、粟酒裂殖酵母、清酒酵母、黑曲霉和萱草絲衣霉菌能夠催化酮泛解酸內(nèi)酯形成D-泛解酸內(nèi)酯。1987 年SHIMIZU S等利用氧化還原系統(tǒng)從消旋化的泛解酸內(nèi)酯出發(fā)，經(jīng)諾卡式菌選擇性氧化L-泛解酸內(nèi)酯生成酮泛解酸內(nèi)酯，后者經(jīng)**滑假絲酵母不對稱還原成D-泛解酸內(nèi)酯。D-泛酸鈣具有補(bǔ)充人體內(nèi)維生素B需求和增強(qiáng)食品風(fēng)味兩方面功效。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="大量供應(yīng)泛解酸內(nèi)酯599-04-2,泛解酸內(nèi)酯" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336219531250/8019769.png"></div><p style="text-indent:25px">醇脫氫酶參與的化學(xué)酶法合成D-泛解酸內(nèi)酯與D- 泛解酸內(nèi)酯的工業(yè)合成類似，從縮醛反應(yīng)出發(fā)再經(jīng)醇脫氫酶還原， *經(jīng)過三步就合成了D- 泛解酸內(nèi)酯。這種醇脫氫酶參與的化學(xué)酶法合成過程由德國比勒費(fèi)爾德大學(xué)HEIDLINDEMANN M 等在2015 年設(shè)計(jì)以異丁醛和乙醛酸乙酯為起始原料，以L-組氨酸作為有機(jī)催化劑在酸性條件下發(fā)生醛醛縮合反應(yīng)，得到(R)-中間體1。醇脫氫酶以異丙醇為輔底物實(shí)現(xiàn)輔酶循環(huán)，將中間體1 還原成中間體2，中間體2 無需分離直接自發(fā)環(huán)化成D-泛解酸內(nèi)酯。反應(yīng)中D-泛解酸內(nèi)酯的總得率達(dá)55%，產(chǎn)物e.e.值達(dá)到95%。中文別名:二氫-3-羥基-4,4-二甲基-2(3H)呋喃酮。大量供應(yīng)泛解酸內(nèi)酯599-04-2</p><p style="text-indent:25px">中文別名:D-泛解酸內(nèi)酯。大量供應(yīng)泛解酸內(nèi)酯599-04-2</p><p> D-泛酸鈣，化學(xué)名為N-(α,γ-二羥基-β,β-二甲基丁酰)-β-氨基丙酸鈣，俗稱維生素B5，是輔酶A的組成部分，它是人體和動(dòng)物維持正常生理機(jī)能不可缺少的物質(zhì)，廣泛應(yīng)用于飼料、醫(yī)藥、食品等工業(yè)。 </p> <p> D-泛醇，俗稱維生素原B5，是一種優(yōu)異的皮膚與頭發(fā)保護(hù)劑，可使皮膚保持柔嫩、毛發(fā)光亮油潤，廣泛應(yīng)用在護(hù)發(fā)產(chǎn)品和化妝品中，還可用于醫(yī)藥、保健食品等領(lǐng)域。 </p> <p> D-泛酸鈣的制備方法主要有以下兩種。 </p> <p> 一種是先化學(xué)合成DL-泛酸鈣，通過拆分DL-泛酸鈣而制得D-泛酸鈣。 </p> <p> 另一種是通過化學(xué)法或生物法拆分關(guān)鍵中間體DL-泛解酸內(nèi)酯得到D-泛解酸內(nèi)酯，再由D-泛解酸內(nèi)酯與β--氨基丙酸反應(yīng)合成D-泛酸鈣。 </p> <p> D-泛醇由D-泛解酸內(nèi)酯與β--氨基丙醇反應(yīng)制得。 </p> <p> <br /> 大量供應(yīng)泛解酸內(nèi)酯599-04-2</p><p style="text-indent:25px">上海臨辰醫(yī)藥科技有限公司成立于2016-04-05，專業(yè)Plasdone?聚維酮(PVP)，Polyplasdone?交聯(lián)聚維酮(PVPP)，Plasdone?共聚維酮（PVP/VA)，Benecel?羥丙甲纖維素(HPMC)，Klucel?羥丙纖維素(HPC) 硬脂富馬酸鈉，羧甲基淀粉鈉，交聯(lián)羧甲基纖維素鈉，微晶纖維素，磷酸氫鈣（無水/二水）USP-NF,Ph.Eur,JP" D-(+)-半乳糖（植物）蔗糖，異麥芽糖，異麥芽酮糖醇，三氯蔗糖，環(huán)氨酸鈉（甜蜜素)，赤蘚糖醇丁香酚，丁香油，蓖麻油，芝麻油，橄欖油，中鏈甘油三酸酯，乙酰單酸甘油乙酯，蔗糖脂肪酸酯聚乙二醇3350/1000/4000/6000/8000，白陶土，液體石蠟，輕質(zhì)液體石蠟，（干燥）氫氧化鋁凝膠，薄荷腦，合成鋁碳酸鎂，合成硅酸鋁，氧化鎂，氫氧化鎂，甘羥鋁，甘氨酸鋁，磷酸鈣（二水/無水），三硅酸鎂，滑石粉，BHA,BHT,多庫酯鈉，組氨酸，鹽酸組氨酸，精氨酸，鹽酸精氨酸，絲氨酸，半胱氨酸，丙氨酸， Pfanstiehl海藻糖（二水），蔗糖（甘蔗/甜菜），甘露醇，精氨酸，琥珀酸二鈉（無水），氨丁三醇 (含低內(nèi)*素），活性炭（供注射）色素系列黃/紅氧化鐵，檸檬黃色淀，等多項(xiàng)業(yè)務(wù)，主營業(yè)務(wù)涵蓋[ "泛解酸內(nèi)酯", "有機(jī)可可粉有機(jī)果粉", "阿拉伯膠瓜爾膠 ", "BIS TRIS " ]。唯才是舉，唯能是用：擁有優(yōu)秀人才5~10人和，是實(shí)現(xiàn)企業(yè)戰(zhàn)略目標(biāo)的基礎(chǔ)，是企業(yè)持續(xù)發(fā)展的動(dòng)力。公司以誠信為本，業(yè)務(wù)領(lǐng)域涵蓋[ "泛解酸內(nèi)酯", "有機(jī)可可粉有機(jī)果粉", "阿拉伯膠瓜爾膠 ", "BIS TRIS " ]，我們本著對客戶負(fù)責(zé)，對員工負(fù)責(zé)，更是對公司發(fā)展負(fù)責(zé)的態(tài)度，爭取做到讓每位客戶滿意。一直以來公司堅(jiān)持以客戶為中心、[ "泛解酸內(nèi)酯", 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