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class="leftbox clearfix"><h1>Pantolactone泛解酸內(nèi)酯值得信賴上海臨辰供應(yīng)</h1><div id="2vubfmt" class="proBig"><div id="d8kgcz8" class="bigimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336147089843/7803549.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div><div id="mspm3d3" class="smallimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336147089843/7803549.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="vz8y2zo" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>Pantolactone泛解酸內(nèi)酯值得信賴,泛解酸內(nèi)酯</p><p><span>***更新：</span>2020-07-08 15:31:01</p><p><span id="click" >瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="8yvxp3k" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海臨辰醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>葉海岑</p><p><span>郵箱: </span>info@linchenpharm.com</p><p><span>電話: </span>13761181955</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span></p><p><span>手機(jī): </span>021-31606595</p><p><span>地址: </span>辰花路5088弄221號</p><p>[當(dāng)前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="2lwykry" class="page-proshow02"><p class="title">詳細(xì)說明</p><div id="osphe8u" class="box"><p><p> 傳統(tǒng)的生產(chǎn)方法是化學(xué)拆分法或鈣鹽誘導(dǎo)結(jié)晶法?；瘜W(xué)拆分的缺點(diǎn)是拆分劑太貴，分離困難，步驟多，成本高，還0性和環(huán)境污染問題。鈣鹽誘導(dǎo)結(jié)晶法步驟多，收率低，投資大，擴(kuò)大生產(chǎn)規(guī)模比較困難。另外，誘導(dǎo)結(jié)晶法不能用于D－泛醇等泛酸衍生物生產(chǎn)，Pantolactone泛解酸內(nèi)酯值得信賴。 </p> <p> “微生物酶法拆分制備D－泛解酸內(nèi)酯及用于生產(chǎn)D－泛酸鈣與D－泛醇”項(xiàng)目選育了一株能高產(chǎn)立體專一性D－泛解酸內(nèi)酯水解酶、不利用不降解泛解酸內(nèi)酯或泛解酸的微生物菌株串珠鐮孢霉，建立了國際**的霉菌交聯(lián)原位固定化方法，酶轉(zhuǎn)化時間短到3～5小時，Pantolactone泛解酸內(nèi)酯值得信賴，效率高，反復(fù)分批酶轉(zhuǎn)化可達(dá)180次以上，Pantolactone泛解酸內(nèi)酯值得信賴，所得到的酶水解產(chǎn)物光學(xué)純度達(dá)到99％e．e．以上，因此具有較好的技術(shù)經(jīng)濟(jì)競爭力。中文別名:(3R)-二氫-3-羥基-4,4-二甲基-2(3H)-呋喃酮。Pantolactone泛解酸內(nèi)酯值得信賴</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="Pantolactone泛解酸內(nèi)酯值得信賴,泛解酸內(nèi)酯" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278336147089843/7803549.png"></div><p> D-泛酸鈣的制備方法主要有兩種：1)先化學(xué)合成DL-泛酸鈣，通過拆分DL-泛酸鈣而制得D-泛酸鈣。2)通過化學(xué)法或生物法拆分關(guān)鍵中間體DL-泛解酸內(nèi)酯得到D-泛解酸內(nèi)酯，再由D-泛解酸內(nèi)酯與β--氨基丙酸反應(yīng)合成D-泛酸鈣，其中生物法拆分的成本比化學(xué)法拆分的成本低15%。 </p> <p> 國外D-泛酸鈣生產(chǎn)公司主要有日本制藥精細(xì)化學(xué)品公司、德國BASF公司、荷蘭DSM公司等。BASF、DSM均采用化學(xué)法生產(chǎn)，而日本***制藥采用生物法酶拆分工藝制備中間體D-泛解酸內(nèi)酯，這也是目前**技術(shù)的工藝。國內(nèi)原只有鑫富藥業(yè)一家有生物法酶拆分工藝，但現(xiàn)在山東新發(fā)也采用了這一工藝。 </p> <p> <br /> Pantolactone泛解酸內(nèi)酯值得信賴化合物中文學(xué)名 D-(-)-泛酰內(nèi)酯。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="Pantolactone泛解酸內(nèi)酯值得信賴,泛解酸內(nèi)酯" src="https://tyunfile.71360.com/WaterMark/UploadFile//637280289509208985/415071.png"></div><p> D-泛酸在生物體內(nèi)的代謝途徑已經(jīng)確定，即經(jīng)α-酮異戊酸，利用酮泛解酸羥甲基轉(zhuǎn)移酶生成酮泛解酸，再利用酮泛解酸還原酶形成泛解酸，***與β-丙氨酸形成D-泛酸。目前，國內(nèi)對維生素B5 的年需求量達(dá)2 000 t 以上，而全球年需求量達(dá)10 000 t以上 </p> <p> 化學(xué)法合成D-泛解酸內(nèi)酯，從低廉原料出發(fā)經(jīng)多步反應(yīng)合成，工藝成熟，但總體存在化學(xué)條件 </p> <p> 嚴(yán)苛、酸堿用量大和能耗較高等問題。生物技術(shù)的發(fā)展為生物酶法合成D-泛解酸內(nèi)酯提供了充分的可行性。目前工業(yè)化合成D-泛解酸內(nèi)酯采用的是化學(xué)法與水解酶拆分法相結(jié)合的技術(shù)路線。 </p> <p> <br /> </p><p> 國外D-泛酸鈣、D-泛醇生產(chǎn)公司主要有日本***制藥精細(xì)化學(xué)品公司、德國BASF公司、荷蘭DSM公司等。國外BASF、DSM均采用化學(xué)法生產(chǎn)，而日本***制藥采用生物法酶拆分工藝制備中間體D-泛解酸內(nèi)酯，這也是目前**技術(shù)的工藝。 </p> <p> D-泛酸、D-泛醇是一種重要的維生素***、食品添加劑和飼料添加劑，用途廣、市場需求量很大。世界上主要的泛酸生產(chǎn)廠家有Roche、BASF和日本***制藥。傳統(tǒng)的生產(chǎn)方法是化學(xué)拆分法或鈣鹽誘導(dǎo)結(jié)晶法。化學(xué)拆分的缺點(diǎn)是拆分劑太貴，分離困難，步驟多，成本高，還0性和環(huán)境污染問題。鈣鹽誘導(dǎo)結(jié)晶法步驟多，收率低，投資大，擴(kuò)大生產(chǎn)規(guī)模比較困難。另外，誘導(dǎo)結(jié)晶法不能用于D-泛醇等泛酸衍生物生產(chǎn)。 </p> <p> <br /> 用微生物酶將 D, L-泛解酸內(nèi)酯拆分得到 D-泛解酸內(nèi)酯，與 B再一丙氨酸鈣縮合生產(chǎn) D-泛酸鈣。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="Pantolactone泛解酸內(nèi)酯值得信賴,泛解酸內(nèi)酯" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637278338760781250/415124.png"></div><p style="text-indent:25px">泛酸,即維生素B5,***存在于生物界中,是動物體內(nèi)合成輔酶A的主要原料,其主要作用是參與糖、脂肪和蛋白質(zhì)的代謝,***應(yīng)用于醫(yī)藥、飼料和食品等領(lǐng)域。D-泛解酸內(nèi)酯是D-泛酸合成過程中重要的手型中間體,生產(chǎn)D-泛酸的關(guān)鍵技術(shù)是DL-泛解酸內(nèi)酯的手性拆分技術(shù)。對比采用昂貴手性拆分劑的化學(xué)拆分方法,微生物酶法拆分具有原料成本低,條件溫和,易于操作,環(huán)境友好等優(yōu)點(diǎn)。通過比較各種生物法的拆分路線,本課題采用選擇性水解D型內(nèi)酯的路線,即用D-立體專一內(nèi)酯水解酶水解消旋內(nèi)酯中的D-泛解酸內(nèi)酯,得到D-泛解酸,再通過內(nèi)酯化得到D-泛解酸內(nèi)酯,而L-泛解酸內(nèi)酯經(jīng)過消旋化可以反復(fù)使用。D-泛解酸內(nèi)酯的市場供應(yīng)商現(xiàn)狀。低水分泛解酸內(nèi)酯發(fā)酵</p><p style="text-indent:25px">DL-泛解酸內(nèi)酯再在串珠鐮孢霉菌的作用下生成D-泛解酸，經(jīng)內(nèi)酯化獲得D-泛解酸內(nèi)酯。Pantolactone泛解酸內(nèi)酯值得信賴</p><p> 泛解酸內(nèi)酯對環(huán)境可能有危害，對水體應(yīng)給予特別注意。 </p> <p> 泛解酸內(nèi)酯是混旋泛酸鈣的中間體。 </p> <p> 泛解酸內(nèi)酯沸點(diǎn)（oC,1.01kpa）：120-122（2kpa） </p> <p> 泛解酸內(nèi)酯相對密度(d204) ：1.65。 </p> <p> 泛解酸內(nèi)酯閃點(diǎn)（oC）：120~122。 </p> <p> 泛解酸內(nèi)酯熔點(diǎn)（℃）：91。 </p> <p> D-(-)-Pantolactone </p> <p> D-(-)-泛酰內(nèi)酯 </p> <p> 食品安全國家標(biāo)準(zhǔn)：食品營養(yǎng)強(qiáng)化劑 D-泛酸鈣適用于以β-氨基丙酸鈣和D-泛解酸內(nèi)酯經(jīng)?；磻?yīng)而得的營養(yǎng)強(qiáng)化劑D-泛酸鈣。 </p> <p> <br /> </p> <p> <br /> </p> <p> D-泛酸鈣具有補(bǔ)充人體內(nèi)維生素B需求和增強(qiáng)食品風(fēng)味兩方面功效。 </p> <p> 食品加工領(lǐng)域?qū)-泛酸鈣用于制作各種營養(yǎng)保健品。 </p> <p> 泛酸鈣具有緩沖***苦味的作用。 Pantolactone泛解酸內(nèi)酯值得信賴</p><p style="text-indent:25px">上海臨辰醫(yī)藥科技有限公司于2016-04-05成立，注冊資本100-200萬元元，現(xiàn)有專業(yè)技術(shù)人員5~10人人，各種專業(yè)人員齊備。在上海臨辰醫(yī)藥近多年發(fā)展歷史，公司旗下現(xiàn)有品牌Domanchem,多曼,NEXIRA,Ashland,BASF,Evonik,ROQUETTE,DFE,JBCOCO,JRS,BENOE,GIFU,StrahlPitsch,CYCLOLAB,SDFine,Avantor,Sudeep,Ambuja,Animo,kyowa-chem,caps-roxlor,MSI,CABOT,Danisco,DoPant,Sasol,Seppic,Clariant,Solvay,EASTMAN,DSM,Pfanstiehl,ANGUS,Cargill,Hopax,IMERYS,KEONOS,KIMICA,LYSI,MERCK,SABINSA,Vertellus,Watson等。公司堅持以客戶為中心、Plasdone?聚維酮(PVP)，Polyplasdone?交聯(lián)聚維酮(PVPP)，Plasdone?共聚維酮（PVP/VA)，Benecel?羥丙甲纖維素(HPMC)，Klucel?羥丙纖維素(HPC) 硬脂富馬酸鈉，羧甲基淀粉鈉，交聯(lián)羧甲基纖維素鈉，微晶纖維素，磷酸氫鈣（無水/二水）USP-NF,Ph.Eur,JP" D-(+)-半乳糖（植物）蔗糖，異麥芽糖，異麥芽酮糖醇，三氯蔗糖，環(huán)氨酸鈉（甜蜜素)，赤蘚糖醇丁香酚，丁香油，蓖麻油，芝麻油，橄欖油，中鏈甘油三酸酯，乙酰單酸甘油乙酯，蔗糖脂肪酸酯聚乙二醇3350/1000/4000/6000/8000，白陶土，液體石蠟，輕質(zhì)液體石蠟，（干燥）氫氧化鋁凝膠，薄荷腦，合成鋁碳酸鎂，合成硅酸鋁，氧化鎂，氫氧化鎂，甘羥鋁，甘氨酸鋁，磷酸鈣（二水/無水），三硅酸鎂，滑石粉，BHA,BHT,多庫酯鈉，組氨酸，鹽酸組氨酸，精氨酸，鹽酸精氨酸，絲氨酸，半胱氨酸，丙氨酸， Pfanstiehl海藻糖（二水），蔗糖（甘蔗/甜菜），甘露醇，精氨酸，琥珀酸二鈉（無水），氨丁三醇 (含低內(nèi)*素），活性炭（供注射）色素系列黃/紅氧化鐵，檸檬黃色淀，市場為導(dǎo)向，重信譽(yù)，保質(zhì)量，想客戶之所想，急用戶之所急，全力以赴滿足客戶的一切需要。誠實(shí)、守信是對企業(yè)的經(jīng)營要求，也是我們做人的基本準(zhǔn)則。公司致力于打造***的[ "泛解酸內(nèi)酯", "有機(jī)可可粉有機(jī)果粉", "阿拉伯膠瓜爾膠 ", "BIS TRIS " ]。</p></p><br /><p>文章來源地址: http://www.cdcfah.com/cp/537419.html</p></div></div></div></div></div><div id="3pb2umo" class="page-right twoColRt"><div id="masp78h" class="box01 margin10 clearfix"><h3><a href="http://www.cdcfah.com/cp/">猜你喜歡</a></h3><div id="ts3xpmz" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/814588.html"><div><img src="http://tyunfile.71360.com/UpLoadFile/2019/11/1/14/637082168864691056_lgpj_5374157.jpg" alt="福建ZF配件哪家強(qiáng) 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