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class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637291455777636719/5338422.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div><div id="apbt2zj" class="smallimg"><div><p class="pic"><img src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637291455777636719/5338422.png" class="vcenter" onerror="javascript:this.src='/static/new_net_01/images/nopic.jpg';"></p></div></div></div><div id="vk8urtv" class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>內(nèi)蒙古蜂毒,蜂毒</p><p><span>***更新：</span>2020-08-09 18:06:52</p><p><span id="click" >瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="et4iuln" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海臨辰醫(yī)藥科技有限公司</a></p><p><span>聯(lián)系人：</span>葉海岑</p><p><span>郵箱: </span>info@linchenpharm.com</p><p><span>電話: </span>13761181955</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span></p><p><span>手機: </span>021-31606595</p><p><span>地址: </span>辰花路5088弄221號</p><p>[當(dāng)前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="gqvc3um" class="page-proshow02"><p class="title">詳細說明</p><div id="7d7zli2" class="box"><p><p> ***鎮(zhèn)痛作用蜂毒中的單體多肽是***的主要成分，它具有類***樣的作用，但無***的不良反應(yīng)t 。蜂毒肽對前列腺素合成酶的***作用是吲哚美辛的7Il倍，故有 </p> <p> 較好的鎮(zhèn)痛***作用l|J。鎮(zhèn)痛強度為***的40％．是安替比林的68倍、鎮(zhèn)痛作用的持續(xù)時間亦較長，內(nèi)蒙古蜂毒，但無水揚酸類對消化道的刺激和甾體類的免疫***作用 </p> <p> 對內(nèi)分秘系統(tǒng)的作用蜂毒對垂體腎上腺皮質(zhì)系統(tǒng)有明顯的興奮作用，內(nèi)蒙古蜂毒，內(nèi)蒙古蜂毒，能使腎上腺皮質(zhì)***和促腎上腺皮質(zhì)***ACTH釋放增加，起到抗風(fēng)濕、類風(fēng)濕莢節(jié)炎作用。 </p> <p> <br /> 蜂毒中富含的酶類等活性物質(zhì)能***凝血活酶活性并能***凝血酶原***物生成。內(nèi)蒙古蜂毒</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="內(nèi)蒙古蜂毒,蜂毒" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637291455777636719/5338422.png"></div><p> 蜂毒肽***作用 </p> <p> 細菌對目前臨床上使用的傳統(tǒng)***素有很強的耐藥性，人們尋找新的***素已十分緊迫。植物、動物和其他生物體內(nèi)存在一些特殊的***多肽，是一類既古老而仍很有效的廣譜***素，這類多肽含有較多的堿性氨基酸，又稱陽離子***肽。由于陽離子多肽與細菌細胞膜結(jié)合的特異性不高，細菌不易通過簡單的變異或修飾多肽產(chǎn)生耐藥性。因此，這類多肽作為抗耐藥細菌的新一代***素已引起人們的重視。由26個氨基酸組成的蜂毒肽和人工合成的類似物也是具有高***活性和溶血活性的陽離子廣譜***肽。蜂毒肽能***2~30種革蘭氏陽性和陰***原微生物的生長繁殖，并能對抗耐藥的金黃色葡萄球菌，還能增強磺胺類和青霉素類***的***能力。內(nèi)蒙古蜂毒蜂毒是蜜蜂極為珍貴的資源(一只工蜂只有0.3毫克左右蜂毒)。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="內(nèi)蒙古蜂毒,蜂毒" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637291455644853516/2042976.png"></div><p> 三、取毒方法 </p> <p> <br /> </p> <p> 電刺激法取蜂毒先要用金屬絲制作一個柵狀網(wǎng)，柵狀網(wǎng)的下面繃一層薄膜，薄膜下面再安裝一個玻璃板用于收集蜂毒，然后將柵狀網(wǎng)與直流電源連接好，電源要求可調(diào)節(jié)電壓并能控制開關(guān)，取毒時將取毒器安置在蜂箱門口并驅(qū)趕工蜂爬上取毒器，工蜂受到電刺激會蟄刺和排毒并將毒液排在玻璃板上。 </p> <p> <br /> </p> <p> 蜜蜂 </p> <p> <br /> </p> <p> 四、臨床應(yīng)用 </p> <p> <br /> </p> <p> 蜂毒的主要成分是蜂毒肽、蜂毒明肽及組織胺、多巴胺等，其中蜂毒肽有***、抗輻射、***及鎮(zhèn)痛等作用，而蜂毒明肽能***神經(jīng)興奮并能***、強心及抗心律失常，因此蜂毒*****的應(yīng)用是用于***風(fēng)濕性關(guān)節(jié)炎、類風(fēng)濕性關(guān)節(jié)炎及腰椎間盤突出癥等病癥，另外蜂毒也常被制成面膜來美容養(yǎng)顏。 </p> <p> <br /> </p> <p> 總結(jié)：蜂毒因產(chǎn)量稀缺且價格昂貴而被譽為“液體黃金”，原因是一只成年工蜂體內(nèi)只有0.3毫克左右蜂毒，也就是說要10000～15000只工蜂才能生產(chǎn)出1克精制蜂毒，因此單從產(chǎn)量上來看蜂毒價格昂貴也就不足為奇了。 </p><p> 1972年，Habermant報道1μmol/L的蜂毒肽就能阻止**細胞增殖但卻不***正常細胞的生長與克隆率。 </p> <p> <br /> </p> <p> 1983年，Vlasak等用mRNA-DNA逆轉(zhuǎn)錄的方法，利用質(zhì)粒pBR322構(gòu)建了蜂王毒腺的cDNA文庫，用蜂王毒腺總mRNA制作探針從此文庫中分離得到了蜂毒肽的cDNA，再進一步將其克隆到質(zhì)粒pUC18上進行DNA序列分析，由DNA的序列分析結(jié)果推測出的蜂毒肽序列與實際測得的完全相同。 </p> <p> <br /> </p> <p> 1996年，Arora通過對正常大鼠肝細胞與大鼠肝*細胞抗缺氧損傷能力的實驗對比，證實蜂毒肽***磷脂酶A2(PLA2)能夠解除肝*細胞對缺氧的抵抗。DUnn等將來自于鼠抗人骨髓瘤細胞和淋巴瘤細胞表面特異蛋白的抗體SCFV基因同蜂毒肽基因相融合，構(gòu)建了能殺**細胞的抗***基因，大腸桿菌中融合基因并表達，精制的抗***顯示了體外殺死**細胞的效能。 Kindas等從處女蜂王的毒腺中提取得到了總mRNA，發(fā)現(xiàn)蜂毒肽mRNA含大約400個堿基對和1個短的polyA尾。 Haase實驗表明蜂毒肽可以***細胞脂酶，包括磷脂酶C(PLC)、磷脂酶D(PLD)、磷脂酶A2(PLA2)及甘油三酯酶等。國外已有蜂***、蜂散痛、蜂特靈等多種蜂毒制劑。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="內(nèi)蒙古蜂毒,蜂毒" src="https://tyunfile.71360.com/WaterMark/UploadFile/shlinchen/637291455865380860/5890055.png"></div><p> 蜂毒肽 (meittin)由26個氨基酸殘基構(gòu)成，但它不是rnRNA直接表達的產(chǎn)物。**初rnRNA翻譯產(chǎn)物是Pre -Promelittin有70個氨基酸，蜂毒肽(meittin)位于COOH一端(第44-69)，N一端開始于疏水的“pre”區(qū)，共21個殘基，接下來是獨物的“Pro”區(qū)，只含有Ala、Pro及酸性殘基。Pre-promelittin需經(jīng)過三步翻譯后的加工過程，才能**終形成蜂毒肽 (meittin) </p> <p> <br /> </p> <p> 明蜂毒肽對超氧陰離子和羥自由基均有很好的***作用。蜂毒肽對超氧陰離子具有一定的***作用，呈現(xiàn)明顯的量效關(guān)系。蜂毒肽對于·OH的***作用效果明顯。蜂毒肽(mPlilfin是蜂毒中起藥理作用和生物學(xué)活性的主要組分。內(nèi)蒙古蜂毒</p><p style="text-indent:25px">蜂毒中富含的蜂毒肽等能直接殺傷**細胞并能增強人體應(yīng)激能力。內(nèi)蒙古蜂毒</p><p> 2001年，黃雪強等通過人白血病細胞觀察蜂毒肽促凋亡的作用，結(jié)果發(fā)現(xiàn)對白血病細胞5mg/mL蜂毒肽作用4h與4μg/mL蜂毒肽作用24h都可見典型凋亡特征，進一步實驗發(fā)現(xiàn)其誘導(dǎo)細胞凋亡同bcl-2基因表達***下降相關(guān)。 </p> <p> 王秋波等通過人工合成含特異性酶切位點的AB兩條寡核苦酸片段，在Klenow酶作用下形成目的基因，用限制型內(nèi)切酶HindⅢ，XmnⅠ同時酶切目的基因和表達載體Pmal-p2質(zhì)粒，在T4連接酶的作用下構(gòu)建兩者的重組體，通過α-互補篩選出附性克隆，并通過特異性酶切和測序分析進行鑒定，獲得重組蜂毒肽的原核表達克隆。內(nèi)蒙古蜂毒</p><p style="text-indent:25px">上海臨辰醫(yī)藥科技有限公司創(chuàng)辦于2016-04-05，是一家貿(mào)易型的公司。經(jīng)過多年不斷的歷練探索和創(chuàng)新發(fā)展，是一家私營有限責(zé)任公司企業(yè)，隨著市場的發(fā)展和生產(chǎn)的需求，與多家企業(yè)合作研究，在原有產(chǎn)品的基礎(chǔ)上經(jīng)過不斷改進，追求新型，在強化內(nèi)部管理，完善結(jié)構(gòu)調(diào)整的同時，優(yōu)良的質(zhì)量、合理的價格、完善的服務(wù)，在業(yè)界受到***好評。以滿足顧客要求為己任；以顧客永遠滿意為標準；以保持行業(yè)**為目標，提供***的[ "泛解酸內(nèi)酯", "有機可可粉有機果粉", "阿拉伯膠瓜爾膠 ", "BIS TRIS " ]。上海臨辰醫(yī)藥將以真誠的服務(wù)、創(chuàng)新的理念、***的產(chǎn)品，為彼此贏得全新的未來！</p></p><br /><p>文章來源地址: http://www.cdcfah.com/cp/861896.html</p></div></div></div></div></div><div id="yscei7r" class="page-right twoColRt"><div id="kumolcg" class="box01 margin10 clearfix"><h3><a href="http://www.cdcfah.com/cp/">猜你喜歡</a></h3><div id="lvs8rcz" class="recomPic likePro"><a href="http://www.cdcfah.com/cp/814588.html"><div><img 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